7PNW
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![BU of 7pnw by Molmil](/molmil-images/mine/7pnw) | Mouse mitochondrial ribosome small subunit lacking m5U modification | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7PNU
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![BU of 7pnu by Molmil](/molmil-images/mine/7pnu) | Assembly intermediate of mouse mitochondrial ribosome small subunit without mS37 in complex with RbfA inward conformation | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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1RLH
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![BU of 1rlh by Molmil](/molmil-images/mine/1rlh) | Structure of a conserved protein from Thermoplasma acidophilum | Descriptor: | SODIUM ION, conserved hypothetical protein | Authors: | Cuff, M.E, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-11-25 | Release date: | 2004-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of a conserved protein from T. acidophilum To be Published
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7PO1
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![BU of 7po1 by Molmil](/molmil-images/mine/7po1) | Initiation complex of human mitochondrial ribosome small subunit with IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7PNV
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![BU of 7pnv by Molmil](/molmil-images/mine/7pnv) | Assembly intermediate of mouse mitochondrial ribosome small subunit without mS37 in complex with RbfA and Mettl15 | Descriptor: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine methyltransferase, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Khawaja, A, Laptev, I, Sergiev, P, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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3P7F
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![BU of 3p7f by Molmil](/molmil-images/mine/3p7f) | Structure of the human Langerin carbohydrate recognition domain | Descriptor: | C-type lectin domain family 4 member K, CALCIUM ION | Authors: | Skerra, A, Schiefner, A. | Deposit date: | 2010-10-12 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The carbohydrate recognition domain of Langerin reveals high structural similarity with the one of DC-SIGN but an additional, calcium-independent sugar-binding site. Mol.Immunol., 45, 2008
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3PGA
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![BU of 3pga by Molmil](/molmil-images/mine/3pga) | STRUCTURAL CHARACTERIZATION OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE | Descriptor: | GLUTAMINASE-ASPARAGINASE | Authors: | Lubkowski, J, Wlodawer, A, Ammon, H.L, Copeland, T.D, Swain, A.L. | Deposit date: | 1994-07-19 | Release date: | 1994-12-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterization of Pseudomonas 7A glutaminase-asparaginase. Biochemistry, 33, 1994
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5D4W
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![BU of 5d4w by Molmil](/molmil-images/mine/5d4w) | Crystal structure of Hsp104 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein | Authors: | Heuck, A, Schitter-Sollner, S, Clausen, T. | Deposit date: | 2015-08-09 | Release date: | 2016-12-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural basis for the disaggregase activity and regulation of Hsp104. Elife, 5, 2016
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5EGR
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![BU of 5egr by Molmil](/molmil-images/mine/5egr) | tRNA guanine transglycosylase (TGT) in complex with an Immucillin derivative | Descriptor: | 1,2-ETHANEDIOL, 2-azanyl-7-[(2~{S},3~{R},5~{S})-5-(hydroxymethyl)-3-oxidanyl-pyrrolidin-2-yl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, GLYCEROL, ... | Authors: | Ehrmann, F.R, Heine, A, Klebe, G. | Deposit date: | 2015-10-27 | Release date: | 2016-11-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Synthesis of an Immucillin Derivative as a Class of tRNA-Guanine Transglycosylase Inhibitors: Exploration of a Transition State Analogous Binding Mode To be Published
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8PFC
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![BU of 8pfc by Molmil](/molmil-images/mine/8pfc) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the zinc finger domain of SPL5 from Arabidopsis thaliana | Descriptor: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION | Authors: | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | Deposit date: | 2023-06-15 | Release date: | 2023-07-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PFD
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![BU of 8pfd by Molmil](/molmil-images/mine/8pfd) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the von Willebrand Factor Type A domain of the proteasomal ubiquitin receptor Rpn10 from Arabidopsis thaliana | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | Authors: | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | Deposit date: | 2023-06-15 | Release date: | 2023-07-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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5AAQ
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![BU of 5aaq by Molmil](/molmil-images/mine/5aaq) | TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy | Descriptor: | CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2, ZINC ION | Authors: | Thurston, T.L, Allen, M.D, Ravenhill, B, Karpiyevitch, M, Bloor, S, Kaul, A, Matthews, S, Komander, D, Holden, D, Bycroft, M, Randow, F. | Deposit date: | 2015-07-28 | Release date: | 2016-07-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy. Embo J., 35, 2016
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4ER0
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![BU of 4er0 by Molmil](/molmil-images/mine/4er0) | Crystal Structure of human DOT1L in complex with inhibitor FED1 | Descriptor: | 5'-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5'-deoxyadenosine, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | Authors: | Wernimont, A.K, Tempel, W, Yu, W, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2012-04-19 | Release date: | 2012-05-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
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4ER7
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![BU of 4er7 by Molmil](/molmil-images/mine/4er7) | Crystal Structure of human DOT1L in complex with inhibitor SGC0947 | Descriptor: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, GLYCEROL, Histone-lysine N-methyltransferase, ... | Authors: | Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2012-04-19 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
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4ETE
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![BU of 4ete by Molmil](/molmil-images/mine/4ete) | Lysozyme, room-temperature, rotating anode, 0.0021 MGy | Descriptor: | CHLORIDE ION, Lysozyme C | Authors: | Boutet, S, Lomb, L, Williams, G, Barends, T, Aquila, A, Doak, R.B, Weierstall, U, DePonte, D, Steinbrener, J, Shoeman, R, Messerschmidt, M, Barty, A, White, T, Kassemeyer, S, Kirian, R, Seibert, M, Montanez, P, Kenney, C, Herbst, R, Hart, P, Pines, J, Haller, G, Gruner, S, Philllip, H, Tate, M, Hromalik, M, Koerner, L, van Bakel, N, Morse, J, Ghonsalves, W, Arnlund, D, Bogan, M, Calemann, C, Fromme, R, Hampton, C, Hunter, M, Johansson, L, Katona, G, Kupitz, C, Liang, M, Martin, A, Nass, K, Redecke, L, Stellato, F, Timneanu, N, Wang, D, Zatsepin, N, Schafer, D, Defever, K, Neutze, R, Fromme, P, Spence, J, Chapman, H, Schlichting, I. | Deposit date: | 2012-04-24 | Release date: | 2012-06-13 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.905 Å) | Cite: | High-resolution protein structure determination by serial femtosecond crystallography. Science, 337, 2012
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7M92
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![BU of 7m92 by Molmil](/molmil-images/mine/7m92) | |
7MH7
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![BU of 7mh7 by Molmil](/molmil-images/mine/7mh7) | |
7PGY
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![BU of 7pgy by Molmil](/molmil-images/mine/7pgy) | Structure of light-adapted AsLOV2 wild type | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Gelfert, R, Weyand, M, Moeglich, A. | Deposit date: | 2021-08-16 | Release date: | 2022-05-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. Nat Commun, 13, 2022
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4APN
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![BU of 4apn by Molmil](/molmil-images/mine/4apn) | Structure of TR from Leishmania infantum in complex with a diarylpirrole-based inhibitor | Descriptor: | 4-[[1-(4-ethylphenyl)-2-methyl-5-(4-methylsulfanylphenyl)pyrrol-3-yl]methyl]thiomorpholine, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Baiocco, P, Ilari, A, Colotti, G, Biava, M. | Deposit date: | 2012-04-04 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
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1XN8
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![BU of 1xn8 by Molmil](/molmil-images/mine/1xn8) | Solution Structure of Bacillus subtilis Protein yqbG: The Northeast Structural Genomics Consortium Target SR215 | Descriptor: | Hypothetical protein yqbG | Authors: | Liu, G, Ma, L, Shen, Y, Acton, T, Atreya, H.S, Xiao, R, Joachimiak, A, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR data collection and analysis protocol for high-throughput protein structure determination. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1A34
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![BU of 1a34 by Molmil](/molmil-images/mine/1a34) | SATELLITE TOBACCO MOSAIC VIRUS/RNA COMPLEX | Descriptor: | PROTEIN (SATELLITE TOBACCO MOSAIC VIRUS), RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... | Authors: | Larson, S.B, Day, J, Greenwood, A.J, McPherson, A. | Deposit date: | 1998-01-28 | Release date: | 1998-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Refined structure of satellite tobacco mosaic virus at 1.8 A resolution. J.Mol.Biol., 277, 1998
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7QGB
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![BU of 7qgb by Molmil](/molmil-images/mine/7qgb) | H. SAPIENS CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6-DIBROMOBENZOTRIAZOLE AT PH 6.5 | Descriptor: | 5,6-DIBROMOBENZOTRIAZOLE, Casein kinase II subunit alpha | Authors: | Winiewska-Szajewska, M, Czapinska, H, Kaus-Drobek, M, Piasecka, A, Mieczkowska, K, Dadlez, M, Bochtler, M, Poznanski, J. | Deposit date: | 2021-12-08 | Release date: | 2022-10-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Competition between electrostatic interactions and halogen bonding in the protein-ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2 alpha complexes. Sci Rep, 12, 2022
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5AH3
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![BU of 5ah3 by Molmil](/molmil-images/mine/5ah3) | |
7JPE
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![BU of 7jpe by Molmil](/molmil-images/mine/7jpe) | Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with m7GpppA Cap-0 and SAM Determined by Fixed-Target Serial Crystallography | Descriptor: | 2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Non-structural protein 10, ... | Authors: | Wilamowski, M, Sherrell, D.A, Minasov, G, Kim, Y, Shuvalova, L, Lavens, A, Chard, R, Rosas-Lemus, M, Maltseva, N, Jedrzejczak, R, Michalska, K, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-08-07 | Release date: | 2020-08-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc.Natl.Acad.Sci.USA, 118, 2021
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5DIV
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![BU of 5div by Molmil](/molmil-images/mine/5div) | The Fk1 domain of FKBP51 in complex with the new synthetic ligand (S)-N-(1-carbamoylcyclopentyl)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamide | Descriptor: | (2S)-N-(1-carbamoylcyclopentyl)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Gaali, S, Feng, X, Sippel, C, Bracher, A, Hausch, F. | Deposit date: | 2015-09-01 | Release date: | 2016-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. J.Med.Chem., 59, 2016
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