5ZIT
 
 | | Crystal structure of human Enterovirus D68 RdRp in complex with NADPH | | Descriptor: | DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp | | Authors: | Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D. | | Deposit date: | 2018-03-17 | | Release date: | 2019-04-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.196 Å) | | Cite: | Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 2020
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7X77
 | | Ectodomain structure of per os infectivity factor 5 | | Descriptor: | Per os infectivity factor 5 | | Authors: | Cao, S, Li, Z, Fu, Y. | | Deposit date: | 2022-03-09 | | Release date: | 2022-06-22 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Characterization of Per Os Infectivity Factor 5 (PIF5) Reveals the Essential Role of Intramolecular Interactions in Baculoviral Oral Infectivity.
J.Virol., 96, 2022
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7WL4
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50 | | Descriptor: | Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide | | Authors: | Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L. | | Deposit date: | 2022-01-12 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors.
Bioorg.Chem., 127, 2022
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9JN8
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3QNO
 | | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite 3tCo | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Polymerase, ... | | Authors: | Xia, S, Wang, M, Wang, J, Konigsberg, W.H. | | Deposit date: | 2011-02-08 | | Release date: | 2012-03-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase.
Biochemistry, 51, 2012
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8WPJ
 | | Anabaena McyI with prebound NAD and soaked NAD | | Descriptor: | McyI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPH
 | | Anabaena McyI with prebound NAD | | Descriptor: | McyI-NAD, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPI
 | | Anabaena McyI with prebound NAD and soaked NADP | | Descriptor: | McyI, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPQ
 | | Anabaena McyI R166M with prebound NAD and citrate | | Descriptor: | CITRATE ANION, McyI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPS
 | | Anabaena McyI R166M with prebound NAD and malate | | Descriptor: | (2S)-2-hydroxybutanedioic acid, McyI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPO
 | | Anabaena McyI R166A with prebound NAD and citrate | | Descriptor: | CITRATE ANION, McyI, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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8WPR
 | | Anabaena McyI R166A with prebound NAD and malate | | Descriptor: | (2S)-2-hydroxybutanedioic acid, GLYCEROL, McyI, ... | | Authors: | Wang, X, Yin, Y, Duan, Y, Liu, L. | | Deposit date: | 2023-10-10 | | Release date: | 2024-10-16 | | Last modified: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural insights into the catalytic mechanism of the microcystin tailoring enzyme McyI.
Commun Biol, 8, 2025
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3TSY
 | | 4-Coumaroyl-CoA Ligase::Stilbene Synthase fusion protein | | Descriptor: | Fusion Protein 4-coumarate--CoA ligase 1, Resveratrol synthase | | Authors: | Yi, H, Jez, J.M. | | Deposit date: | 2011-09-13 | | Release date: | 2011-12-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural and Kinetic Analysis of the Unnatural Fusion Protein 4-Coumaroyl-CoA Ligase::Stilbene Synthase.
J.Am.Chem.Soc., 133, 2011
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6IK4
 | | A Novel M23 Metalloprotease Pseudoalterin from Deep-sea | | Descriptor: | Elastinolytic metalloprotease, GLYCEROL, ZINC ION | | Authors: | Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z. | | Deposit date: | 2018-10-14 | | Release date: | 2019-10-16 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
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7YZ2
 | | Molecular snapshots of drug release from tubulin: 10 milliseconds after photoactivation. | | Descriptor: | Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Wranik, M, Weinert, T, Standfuss, J. | | Deposit date: | 2022-02-18 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Nat Commun, 14, 2023
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7YZ5
 | | Molecular snapshots of drug release from tubulin: 100 milliseconds (steady state) | | Descriptor: | CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wranik, M, Weinert, T, Standfuss, J. | | Deposit date: | 2022-02-18 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Nat Commun, 14, 2023
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3HYF
 | | Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor | | Descriptor: | 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ... | | Authors: | Lansdon, E.B, Kirschberg, T.A. | | Deposit date: | 2009-06-22 | | Release date: | 2009-10-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
J.Med.Chem., 52, 2009
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6RYO
 | | Bacterial membrane enzyme structure by the in meso method at 1.9 A resolution | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, GLYCEROL, ... | | Authors: | Huang, C.Y, Olatunji, S, Bailey, J, Yu, X, Olieric, V, Wang, M, Caffrey, M. | | Deposit date: | 2019-06-11 | | Release date: | 2020-01-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.924 Å) | | Cite: | Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.
Nat Commun, 11, 2020
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7DEO
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | | Authors: | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | | Deposit date: | 2020-11-04 | | Release date: | 2021-03-31 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7DET
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | Authors: | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | | Deposit date: | 2020-11-05 | | Release date: | 2021-03-31 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7XRJ
 | | crystal structure of N-acetyltransferase DgcN-25328 | | Descriptor: | Putative NAD-dependent epimerase/dehydratase family protein, SULFATE ION | | Authors: | Zhang, Y.Z, Yu, Y, Cao, H.Y, Chen, X.L, Wang, P. | | Deposit date: | 2022-05-10 | | Release date: | 2023-02-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Novel D-glutamate catabolic pathway in marine Proteobacteria and halophilic archaea.
Isme J, 17, 2023
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6K2O
 | | Structural basis of glycan recognition in globally predominant human P[8] rotavirus | | Descriptor: | Outer capsid protein VP4, SODIUM ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | | Authors: | Duan, Z, Sun, X. | | Deposit date: | 2019-05-15 | | Release date: | 2019-10-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.296 Å) | | Cite: | Structural Basis of Glycan Recognition in Globally Predominant Human P[8] Rotavirus.
Virol Sin, 35, 2020
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7DEU
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | Authors: | Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. | | Deposit date: | 2020-11-05 | | Release date: | 2021-03-31 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7YZ0
 | | Molecular snapshots of drug release from tubulin: 100 microseconds after photoactivation. | | Descriptor: | Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Wranik, M, Weinert, T, Standfuss, J. | | Deposit date: | 2022-02-18 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Nat Commun, 14, 2023
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7YYZ
 | | Molecular snapshots of drug release from tubulin: 10 microseconds after photoactivation. | | Descriptor: | Azo-Combretastatin A4 (trans), CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Wranik, M, Weinert, T, Standfuss, J. | | Deposit date: | 2022-02-18 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Nat Commun, 14, 2023
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