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6WG4
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BU of 6wg4 by Molmil
Crystal structure of human SMC1-SMC3 hinge domain heterodimer in south-open conformation
Descriptor: Structural maintenance of chromosomes protein, Structural maintenance of chromosomes protein 3
Authors:Shi, Z.B, Yu, H.
Deposit date:2020-04-04
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
6WSL
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BU of 6wsl by Molmil
Cryo-EM structure of VASH1-SVBP bound to microtubules
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Small vasohibin-binding protein, ...
Authors:Li, F, Li, Y, Yu, H.
Deposit date:2020-05-01
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of VASH1-SVBP bound to microtubules.
Elife, 9, 2020
6BNT
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BU of 6bnt by Molmil
Crystal structure of AP2 mu1 adaptin C-terminal domain with IRS-1 peptide
Descriptor: AP-2 complex subunit mu, Insulin receptor substrate 1
Authors:Kikuchi, S, Choi, E, Yu, H.
Deposit date:2017-11-17
Release date:2018-11-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun, 10, 2019
1PKT
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BU of 1pkt by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
1PKS
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BU of 1pks by Molmil
STRUCTURE OF THE PI3K SH3 DOMAIN AND ANALYSIS OF THE SH3 FAMILY
Descriptor: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN
Authors:Koyama, S, Yu, H, Dalgarno, D.C, Shin, T.B, Zydowsky, L.D, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the PI3K SH3 domain and analysis of the SH3 family.
Cell(Cambridge,Mass.), 72, 1993
2UXX
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BU of 2uxx by Molmil
Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct
Descriptor: CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ...
Authors:Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H.
Deposit date:2007-03-30
Release date:2007-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
3DWQ
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BU of 3dwq by Molmil
Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc
Descriptor: AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ...
Authors:Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWA
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BU of 3dwa by Molmil
Crystal structure of the B-subunit of the AB5 toxin from E. coli
Descriptor: PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B
Authors:Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.084 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWP
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BU of 3dwp by Molmil
Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc
Descriptor: N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ...
Authors:Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
6E15
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BU of 6e15 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
6E14
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BU of 6e14 by Molmil
Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD
Descriptor: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ...
Authors:Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H.
Deposit date:2018-07-09
Release date:2018-10-17
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.
Nature, 562, 2018
4K6J
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BU of 4k6j by Molmil
Human cohesin inhibitor WapL
Descriptor: ACETATE ION, SULFATE ION, Wings apart-like protein homolog
Authors:Tomchick, D.R, Yu, H, Ouyang, Z.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6205 Å)
Cite:Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013
3GMH
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BU of 3gmh by Molmil
Crystal Structure of the Mad2 Dimer
Descriptor: Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION
Authors:Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J.
Deposit date:2009-03-13
Release date:2010-11-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
Proc.Natl.Acad.Sci.USA, 112, 2015
1DUJ
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BU of 1duj by Molmil
SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2
Descriptor: SPINDLE ASSEMBLY CHECKPOINT PROTEIN
Authors:Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H.
Deposit date:2000-01-17
Release date:2000-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
3Q6S
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BU of 3q6s by Molmil
The crystal structure of the heterochromatin protein 1 beta chromoshadow domain complexed with a peptide from Shugoshin 1
Descriptor: Chromobox protein homolog 1, Shugoshin-like 1
Authors:Brautigam, C.A, Chaudhary, J, Yu, H.
Deposit date:2011-01-03
Release date:2011-12-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.
Mol Biol Cell, 22, 2011
4N14
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BU of 4n14 by Molmil
Crystal structure of Cdc20 and apcin complex
Descriptor: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog
Authors:Luo, X, Tian, W, Yu, H.
Deposit date:2013-10-03
Release date:2014-08-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
Nature, 514, 2014
4PK7
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BU of 4pk7 by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
Authors:Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
Deposit date:2014-05-13
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
4PJU
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BU of 4pju by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1)
Descriptor: Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
Authors:Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
Deposit date:2014-05-12
Release date:2014-08-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
5T8V
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BU of 5t8v by Molmil
Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment
Descriptor: CITRIC ACID, Putative uncharacterized protein
Authors:Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z.
Deposit date:2016-09-08
Release date:2016-10-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
Proc.Natl.Acad.Sci.USA, 113, 2016
4PJW
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BU of 4pjw by Molmil
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog
Authors:Hara, K, Chen, Z, Tomchick, D.R, Yu, H.
Deposit date:2014-05-12
Release date:2014-08-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
5TO2
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BU of 5to2 by Molmil
Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
Descriptor: DI(HYDROXYETHYL)ETHER, Streptavidin
Authors:Zhang, M, Biswas, S, Deng, W, Yu, H.
Deposit date:2016-10-16
Release date:2017-05-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of streptavidin with one wild type subunit and three mutated subunits (N23A/S27D/S45A)
To Be Published
5UN0
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BU of 5un0 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125
Descriptor: proteasome assembly chaperone 2 (PAC2) homologue Rv2125
Authors:Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H.
Deposit date:2017-01-30
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).
J. Bacteriol., 199, 2017
1KLQ
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BU of 1klq by Molmil
The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20
Descriptor: MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide
Authors:Luo, X, Tang, Z, Rizo, J, Yu, H.
Deposit date:2001-12-12
Release date:2002-01-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.
Mol.Cell, 9, 2002
6OCF
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BU of 6ocf by Molmil
The crystal structure of VASH1-SVBP complex
Descriptor: CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ...
Authors:Li, F, Luo, X, Yu, H.
Deposit date:2019-03-23
Release date:2019-06-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
6OCH
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BU of 6och by Molmil
Crystal structure of VASH1-SVBP complex bound with parthenolide
Descriptor: GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ...
Authors:Li, F, Luo, X, Yu, H.
Deposit date:2019-03-23
Release date:2019-06-26
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019

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