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Crystal Structure of chicken Netrin-1 (LN-LE3) in complex with mouse DCC (FN4-5)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Netrin receptor DCC, ...
Authors:	Xu, K, Nikolov, D.B.
Deposit date:	2014-05-18
Release date:	2014-06-18
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.901 Å)
Cite:	Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science, 344, 2014

7JZ4

Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ...
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2020-09-01
Release date:	2021-05-26
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.747 Å)
Cite:	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021

7JZK

Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain
Descriptor:	LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2020-09-02
Release date:	2021-05-26
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.457 Å)
Cite:	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021

7JZ1

Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
Descriptor:	MGC34 heavy chain, MGC34 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2020-09-01
Release date:	2021-05-26
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.37 Å)
Cite:	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021

7JZI

Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
Descriptor:	LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2020-09-02
Release date:	2021-05-26
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.707 Å)
Cite:	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021

4YN0

Crystal structure of APP E2 domain in complex with DR6 CRD domain
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, MAGNESIUM ION, ...
Authors:	Xu, K, Nikolov, D.
Deposit date:	2015-03-08
Release date:	2015-04-15
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation. Genes Dev., 29, 2015

7XOT

Crystal structure of Keap1_6k
Descriptor:	2-[[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]-[4-(2-diethoxyphosphorylethanoylamino)phenyl]sulfonyl-amino]ethanamide, Kelch-like ECH-associated protein 1
Authors:	Xu, K.
Deposit date:	2022-05-01
Release date:	2023-05-03
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Crystal structure of Keap1_6k To Be Published

3D11

Crystal Structures of the Nipah G Attachment Glycoprotein
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase, ...
Authors:	Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
Deposit date:	2008-05-02
Release date:	2008-08-19
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.306 Å)
Cite:	Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105, 2008

3D12

Crystal Structures of Nipah Virus G Attachment Glycoprotein in Complex with its Receptor Ephrin-B3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-B3, ...
Authors:	Xu, K, Rajashankar, K.R, Chan, Y.P, Himanen, P, Broder, C.C, Nikolov, D.B.
Deposit date:	2008-05-02
Release date:	2008-08-19
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.005 Å)
Cite:	Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc.Natl.Acad.Sci.USA, 105, 2008

5ECD

Structure of the Shigella flexneri VapC mutant D98N crystal form 1
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC
Authors:	Xu, K.
Deposit date:	2015-10-20
Release date:	2016-02-17
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri. Proteins, 84, 2016

5ED0

Structure of the Shigella flexneri VapC mutant D7N
Descriptor:	tRNA(fMet)-specific endonuclease VapC
Authors:	Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:	2015-10-20
Release date:	2016-02-17
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri. Proteins, 84, 2016

5ECY

Structure of the Shigella flexneri VapC mutant D98N crystal form 2
Descriptor:	tRNA(fMet)-specific endonuclease VapC
Authors:	Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:	2015-10-20
Release date:	2016-10-19
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri to be published

5ECW

Structure of the Shigella flexneri VapC mutant D7A
Descriptor:	tRNA(fMet)-specific endonuclease VapC
Authors:	Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:	2015-10-20
Release date:	2016-02-17
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri. Proteins, 84, 2016

5EVM

Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ...
Authors:	Xu, K, Nikolov, D.B.
Deposit date:	2015-11-20
Release date:	2015-12-16
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.367 Å)
Cite:	Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. Plos Pathog., 11, 2015

7LKG

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151
Descriptor:	Circumsporozoite protein, m43.151 Fab Heavy Chain, m43.151 Fab Light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-02-02
Release date:	2021-12-15
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.02 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7LKB

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127
Descriptor:	Circumsporozoite protein, SULFATE ION, m42.127 Fab heavy Chain, ...
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-02-02
Release date:	2021-12-15
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

6UBI

N123-VRC34.05 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor:	HIV fusion peptide 512-519, VRC34.05 heavy chain, VRC34.05 light chain
Authors:	Xu, K, Liu, K, Kwong, P.D.
Deposit date:	2019-09-11
Release date:	2020-03-18
Last modified:	2020-04-22
Method:	X-RAY DIFFRACTION (1.903 Å)
Cite:	VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage. Cell Host Microbe, 27, 2020

7RDA

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138
Descriptor:	Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD9

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159
Descriptor:	Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.91 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD3

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126
Descriptor:	Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.81 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RCS

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160
Descriptor:	Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-08
Release date:	2021-12-15
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

7RD4

Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149
Descriptor:	Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-07-09
Release date:	2021-12-15
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021

6UCE

N123-VRC34_pI3 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor:	HIV fusion peptide, N123-VRC34_pI3 heavy chain, N123-VRC34_pI3 light chain
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2019-09-16
Release date:	2020-03-18
Last modified:	2020-04-22
Method:	X-RAY DIFFRACTION (1.382 Å)
Cite:	VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage. Cell Host Microbe, 27, 2020

7MY2

CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb30, ...
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-05-20
Release date:	2021-06-16
Last modified:	2021-07-28
Method:	ELECTRON MICROSCOPY (2.65 Å)
Cite:	Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature, 595, 2021

7MY3

CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb12, ...
Authors:	Xu, K, Kwong, P.D.
Deposit date:	2021-05-20
Release date:	2021-06-16
Last modified:	2024-10-30
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature, 595, 2021

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