6R0T
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![BU of 6r0t by Molmil](/molmil-images/mine/6r0t) | Getah virus macro domain in complex with ADPr in open conformation | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ... | Authors: | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | Deposit date: | 2019-03-13 | Release date: | 2020-04-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0R
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![BU of 6r0r by Molmil](/molmil-images/mine/6r0r) | Getah virus macro domain in complex with ADPr covalently bond to Cys34 | Descriptor: | 1,2-ETHANEDIOL, Non-structural polyprotein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate | Authors: | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | Deposit date: | 2019-03-13 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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5FVA
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![BU of 5fva by Molmil](/molmil-images/mine/5fva) | Toscana Virus Nucleocapsid Protein | Descriptor: | NUCLEOPROTEIN, SODIUM ION | Authors: | Baklouti, A, Sevajol, M, Goulet, A, Lichiere, J, Ferron, F, Canard, B, Charrel, R.N, Coutard, B, Papageorgiou, N. | Deposit date: | 2016-02-03 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Toscana virus nucleoprotein oligomer organization observed in solution. Acta Crystallogr D Struct Biol, 73, 2017
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2V6I
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![BU of 2v6i by Molmil](/molmil-images/mine/2v6i) | Kokobera Virus Helicase | Descriptor: | PYROPHOSPHATE 2-, RNA HELICASE | Authors: | Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A. | Deposit date: | 2007-07-18 | Release date: | 2008-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Biochemical Analysis of Kokobera Virus Helicase Proteins: Struct., Funct., Bioinf., 70, 2008
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2W5E
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![BU of 2w5e by Molmil](/molmil-images/mine/2w5e) | Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 Angstrom resolution | Descriptor: | CADMIUM ION, CHLORIDE ION, PUTATIVE SERINE PROTEASE | Authors: | Speroni, S, Rohayem, J, Nenci, S, Bonivento, D, Robel, I, Barthel, J, Coutard, B, Canard, B, Mattevi, A. | Deposit date: | 2008-12-10 | Release date: | 2009-03-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution. J.Mol.Biol., 387, 2009
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2XYV
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![BU of 2xyv by Molmil](/molmil-images/mine/2xyv) | Crystal structure of the nsp16 nsp10 SARS coronavirus complex | Descriptor: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | Authors: | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | Deposit date: | 2010-11-19 | Release date: | 2011-10-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2XYR
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![BU of 2xyr by Molmil](/molmil-images/mine/2xyr) | Crystal structure of the nsp16 nsp10 SARS coronavirus complex | Descriptor: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | Authors: | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | Deposit date: | 2010-11-18 | Release date: | 2011-10-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2XYQ
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![BU of 2xyq by Molmil](/molmil-images/mine/2xyq) | Crystal structure of the nsp16 nsp10 SARS coronavirus complex | Descriptor: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | Authors: | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | Deposit date: | 2010-11-18 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2V6J
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![BU of 2v6j by Molmil](/molmil-images/mine/2v6j) | Kokobera Virus Helicase: Mutant Met47Thr | Descriptor: | RNA HELICASE | Authors: | Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A. | Deposit date: | 2007-07-18 | Release date: | 2008-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Biochemical Analysis of Kokobera Virus Helicase Proteins: Struct., Funct., Bioinf., 70, 2008
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3GPO
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![BU of 3gpo by Molmil](/molmil-images/mine/3gpo) | Crystal structure of macro domain of Chikungunya virus in complex with ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 | Authors: | Malet, H, Jamal, S, Coutard, B, Canard, B. | Deposit date: | 2009-03-23 | Release date: | 2009-07-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
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3GQE
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![BU of 3gqe by Molmil](/molmil-images/mine/3gqe) | Crystal structure of macro domain of Venezuelan Equine Encephalitis virus | Descriptor: | BICINE, Non-structural protein 3 | Authors: | Jamal, S, Malet, H, Coutard, B, Canard, B. | Deposit date: | 2009-03-24 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
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3GQO
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![BU of 3gqo by Molmil](/molmil-images/mine/3gqo) | Crystal structure of macro domain of Venezuelan Equine Encephalitis virus in complex with ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 | Authors: | Malet, H, Jamal, S, Coutard, B, Ferron, F, Canard, B. | Deposit date: | 2009-03-24 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
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3GPQ
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![BU of 3gpq by Molmil](/molmil-images/mine/3gpq) | Crystal structure of macro domain of Chikungunya virus in complex with RNA | Descriptor: | Non-structural protein 3, RNA (5'-R(*AP*AP*A)-3') | Authors: | Malet, H, Jamal, S, Coutard, B, Canard, B. | Deposit date: | 2009-03-23 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
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3GPG
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![BU of 3gpg by Molmil](/molmil-images/mine/3gpg) | |
3GZF
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![BU of 3gzf by Molmil](/molmil-images/mine/3gzf) | Structure of the C-terminal domain of nsp4 from Feline Coronavirus | Descriptor: | Replicase polyprotein 1ab, SULFATE ION | Authors: | Manolaridis, I, Wojdyla, J.A, Panjikar, S, Snijder, E.J, Gorbalenya, A.E, Coutard, B, Tucker, P.A. | Deposit date: | 2009-04-07 | Release date: | 2009-08-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.756 Å) | Cite: | Structure of the C-terminal domain of nsp4 from feline coronavirus Acta Crystallogr.,Sect.D, 65, 2009
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4CTJ
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![BU of 4ctj by Molmil](/molmil-images/mine/4ctj) | DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT 3A9 | Descriptor: | 2,3-dihydro-1-benzofuran-5-carboxylic acid, NON-STRUCTURAL PROTEIN 5, S-ADENOSYLMETHIONINE, ... | Authors: | Barral, K, Bricogne, G, Sharff, A. | Deposit date: | 2014-03-14 | Release date: | 2014-04-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Assessment of Dengue Virus Helicase and Methyltransferase as Targets for Fragment-Based Drug Discovery. Antiviral Res., 106, 2014
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4CTK
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![BU of 4ctk by Molmil](/molmil-images/mine/4ctk) | DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT 2A4 | Descriptor: | DIMETHYL SULFOXIDE, POLYPROTEIN, S-ADENOSYLMETHIONINE, ... | Authors: | Barral, K, Bricogne, G, Sharff, A. | Deposit date: | 2014-03-14 | Release date: | 2014-04-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Assessment of Dengue Virus Helicase and Methyltransferase as Targets for Fragment-Based Drug Discovery. Antiviral Res., 106, 2014
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6YU8
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![BU of 6yu8 by Molmil](/molmil-images/mine/6yu8) | RNA Methyltransferase of Sudan Ebola Virus | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Ferron, F, Valle, C, Zamboni, V, Canard, B, Decroly, E. | Deposit date: | 2020-04-25 | Release date: | 2021-02-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.841 Å) | Cite: | First insights into the structural features of Ebola virus methyltransferase activities. Nucleic Acids Res., 49, 2021
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2QEQ
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![BU of 2qeq by Molmil](/molmil-images/mine/2qeq) | |
3CDU
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![BU of 3cdu by Molmil](/molmil-images/mine/3cdu) | Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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3CDW
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![BU of 3cdw by Molmil](/molmil-images/mine/3cdw) | Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. | Deposit date: | 2008-02-27 | Release date: | 2008-07-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
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4NYZ
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![BU of 4nyz by Molmil](/molmil-images/mine/4nyz) | The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution | Descriptor: | GLUTAMINE, GLYCEROL, Genome polyprotein, ... | Authors: | Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N. | Deposit date: | 2013-12-11 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site J.Virol., 88, 2014
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4NZ0
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4Y34
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![BU of 4y34 by Molmil](/molmil-images/mine/4y34) | Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 | Descriptor: | 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... | Authors: | Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. | Deposit date: | 2015-02-10 | Release date: | 2015-04-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
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4Y3C
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![BU of 4y3c by Molmil](/molmil-images/mine/4y3c) | I304V 3D polymerase mutant of EMCV | Descriptor: | 3D polymerase, CHLORIDE ION, GLYCEROL | Authors: | Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L. | Deposit date: | 2015-02-10 | Release date: | 2015-04-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
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