2XYV
Crystal structure of the nsp16 nsp10 SARS coronavirus complex
Summary for 2XYV
Entry DOI | 10.2210/pdb2xyv/pdb |
Related | 1O5S 1P76 1P9T 1PA5 1PUK 1Q1X 1SXF 1UJ1 1UK2 1UK3 1UK4 1UW7 1WOF 1YSY 1Z1I 1Z1J 2A5A 2A5I 2A5K 2ACF 2AHM 2AMD 2AMQ 2BX3 2BX4 2C3S 2D2D 2V6N 2XYQ 2XYR |
Descriptor | PUTATIVE 2'-O-METHYL TRANSFERASE, NON-STRUCTURAL PROTEIN 10, SODIUM ION, ... (8 entities in total) |
Functional Keywords | transferase-viral protein complex, rossmann fold, transferase/viral protein |
Biological source | SARS CORONAVIRUS More |
Cellular location | Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X7 P0C6X7 |
Total number of polymer chains | 2 |
Total formula weight | 46688.40 |
Authors | Decroly, E.,Debarnot, C.,Ferron, F.,Bouvet, M.,Coutard, B.,Imbert, I.,Gluais, L.,Papageorgiou, N.,Ortiz-Lombardia, M.,Lescar, J.,Canard, B. (deposition date: 2010-11-19, release date: 2011-10-26, Last modification date: 2023-12-20) |
Primary citation | Decroly, E.,Debarnot, C.,Ferron, F.,Bouvet, M.,Coutard, B.,Imbert, I.,Gluais, L.,Papageorgiou, N.,Sharff, A.,Bricogne, G.,Ortiz-Lombardia, M.,Lescar, J.,Canard, B. Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7:2059-, 2011 Cited by PubMed: 21637813DOI: 10.1371/JOURNAL.PPAT.1002059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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