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7KHF
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BU of 7khf by Molmil
CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MDB1 Fab heavy chain, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-10-21
Release date:2021-03-31
Last modified:2021-05-05
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
7KFK
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BU of 7kfk by Molmil
Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2020-10-14
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
6UBI
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BU of 6ubi by Molmil
N123-VRC34.05 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide 512-519, VRC34.05 heavy chain, VRC34.05 light chain
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2019-09-11
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6TYB
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BU of 6tyb by Molmil
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Immunity, 51, 2019
6UCE
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BU of 6uce by Molmil
N123-VRC34_pI3 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI3 heavy chain, N123-VRC34_pI3 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.382 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6UCF
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BU of 6ucf by Molmil
N123-VRC34_pI4 HIV neutralizing antibody in complex with HIV fusion peptide residue 512-519
Descriptor: HIV fusion peptide, N123-VRC34_pI4 heavy chain, N123-VRC34_pI4 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2019-09-16
Release date:2020-03-18
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
6URM
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BU of 6urm by Molmil
Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zhou, T, Cheung, S.F, Kwong, P.D.
Deposit date:2019-10-23
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.
Cell Rep, 32, 2020
6VI0
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BU of 6vi0 by Molmil
Cryo-EM structure of VRC01.23 in complex with HIV-1 Env BG505 DS.SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-01-10
Release date:2021-01-13
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.
Mabs, 13
6VRW
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BU of 6vrw by Molmil
Cryo-EM structure of stabilized HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-02-10
Release date:2020-03-11
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.
Cell Rep, 31, 2020
6VZI
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BU of 6vzi by Molmil
Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ...
Authors:Lai, Y.-T, Kwong, P.D.
Deposit date:2020-02-28
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.716 Å)
Cite:Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.
J.Virol., 94, 2020
7SG5
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BU of 7sg5 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var2
Descriptor: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-10-05
Release date:2022-06-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
7SG6
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BU of 7sg6 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var10
Descriptor: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-10-05
Release date:2022-06-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
7MY2
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BU of 7my2 by Molmil
CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb30, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-05-20
Release date:2021-06-16
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7MY3
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BU of 7my3 by Molmil
CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb12, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-05-20
Release date:2021-06-16
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7RDA
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BU of 7rda by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.138
Descriptor: Circumsporozoite protein, antibody m43.138 heavy chain, antibody m43.138 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-07-09
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD9
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BU of 7rd9 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.159
Descriptor: Circumsporozoite protein, antibody m43.159 heavy chain, antibody m43.159 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-07-09
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD3
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BU of 7rd3 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126
Descriptor: Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-07-09
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RAJ
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BU of 7raj by Molmil
Structure of PfCSP peptide 21 with antibody iGL-CIS43.D3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN-ALA-ASN, ZINC ION, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-07-01
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RCS
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BU of 7rcs by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160
Descriptor: Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-07-08
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RD4
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BU of 7rd4 by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149
Descriptor: Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-07-09
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7R73
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BU of 7r73 by Molmil
Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-06-24
Release date:2022-03-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7RI1
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BU of 7ri1 by Molmil
Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Lamma VHH antibody J3, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-07-19
Release date:2022-03-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7RI2
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BU of 7ri2 by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, anti-HIV llama VHH antibody A12
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-07-19
Release date:2022-03-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7R74
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BU of 7r74 by Molmil
Crystal structure of llama VHH antibody in complex with HIV-1 HXBC2 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C8 VHH domain, Glycoprotein 120
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-06-24
Release date:2022-03-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
8EK1
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BU of 8ek1 by Molmil
Cryo-EM structure of a potent anti-malarial antibody L9 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP)(dominant class)
Descriptor: Circumsporozoite protein, L9 Fab heavy chain, L9 Fab light chain
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-09-19
Release date:2023-03-15
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope.
Structure, 31, 2023

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