7KFK

Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain

Summary for 7KFK

• Entry DOI: 10.2210/pdb7kfk/pdb
• Descriptor: Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: lilrb1, rifin, malaria, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 83370.93

Authors

Xu, K.,Kwong, P.D. (deposition date: 2020-10-14, release date: 2021-03-31, Last modification date: 2023-10-18)

• Primary citation: Chen, Y.,Xu, K.,Piccoli, L.,Foglierini, M.,Tan, J.,Jin, W.,Gorman, J.,Tsybovsky, Y.,Zhang, B.,Traore, B.,Silacci-Fregni, C.,Daubenberger, C.,Crompton, P.D.,Geiger, R.,Sallusto, F.,Kwong, P.D.,Lanzavecchia, A.; Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.; Nature, 592:639-643, 2021; PubMed: 33790470; DOI: 10.1038/s41586-021-03378-6

Experimental method

X-RAY DIFFRACTION (2.63 Å)