7KHF

CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain

Summary for 7KHF

• Entry DOI: 10.2210/pdb7khf/pdb
• Related: 7KFK
• EMDB information: 22879
• Descriptor: MDB1 Fab heavy chain, MDB1 Fab light chain, Rifin, ... (5 entities in total)
• Functional Keywords: lilrb1, rifin, malaria, receptor-inserted antibody, mdb1, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 171491.72

Authors

Xu, K.,Kwong, P.D. (deposition date: 2020-10-21, release date: 2021-03-31, Last modification date: 2021-05-05)

• Primary citation: Chen, Y.,Xu, K.,Piccoli, L.,Foglierini, M.,Tan, J.,Jin, W.,Gorman, J.,Tsybovsky, Y.,Zhang, B.,Traore, B.,Silacci-Fregni, C.,Daubenberger, C.,Crompton, P.D.,Geiger, R.,Sallusto, F.,Kwong, P.D.,Lanzavecchia, A.; Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.; Nature, 592:639-643, 2021; PubMed: 33790470; DOI: 10.1038/s41586-021-03378-6

Experimental method

ELECTRON MICROSCOPY (3.54 Å)