5EM4

Structure of CYP2B4 F244W in a ligand free conformation

5EM4 の概要

• エントリーDOI: 10.2210/pdb5em4/pdb
• 関連するPDBエントリー: 1PO5 1SUO 2BDM 2Q6N 3G5N 3G93 3KW4 3ME6 3MVR 3R1A 3R1B 3TK3 3TMZ 3UAS 4H1N 4JLT
• 分子名称: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (4 entities in total)
• 機能のキーワード: cytochrome p450, monooxygenase, oxidoreductase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115109.98

構造登録者

Shah, M.B.,Stout, C.D.,Halpert, J.R. (登録日: 2015-11-05, 公開日: 2016-03-23, 最終更新日: 2023-09-27)

• 主引用文献: Liu, J.,Shah, M.B.,Zhang, Q.,Stout, C.D.,Halpert, J.R.,Wilderman, P.R.; Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.; Biochemistry, 55:1997-2007, 2016; PubMed: 26982502; DOI: 10.1021/acs.biochem.5b01330

実験手法

X-RAY DIFFRACTION (3.02 Å)