2BDM

Structure of Cytochrome P450 2B4 with Bound Bifonazole

Summary for 2BDM

Entry DOI	10.2210/pdb2bdm/pdb
Related	1PO5 1SUO
Descriptor	Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, ... (5 entities in total)
Functional Keywords	p450, monooxygenase, oxidoreductase, membrane protein, cyp 2b4, cyp lm2
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein: P00178
Total number of polymer chains	1
Total formula weight	57695.04
Authors	Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D. (deposition date: 2005-10-20, release date: 2005-12-27, Last modification date: 2023-08-23)
Primary citation	Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D. Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction. J.Biol.Chem., 281:5973-5981, 2006 Cited by PubMed: 16373351 DOI: 10.1074/jbc.M511464200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation