3PBY
Crystal structure of the mutant L123S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
Summary for 3PBY
| Entry DOI | 10.2210/pdb3pby/pdb |
| Related | 3G18 3LHW 3LTP 3LTS 3LTY 3LV5 3LV6 3NQ6 3NQ7 3NQA 3NQC 3NQD 3NQE 3NQF 3NQG 3NQM 3P5Y 3P5Z 3P60 3P61 3PBU 3PBV 3PBW 3PC0 3SIZ 3SY5 |
| Descriptor | Orotidine 5'-monophosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | tim barrel, orotidine 5'-monophosphate decarboxylase, 6-azauridine 5'-monophosphate, lyase |
| Biological source | Methanobacterium thermoautotrophicum |
| Total number of polymer chains | 2 |
| Total formula weight | 50459.67 |
| Authors | Fedorov, A.A.,Fedorov, E.V.,Iiams, V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (deposition date: 2010-10-21, release date: 2011-09-21, Last modification date: 2023-09-06) |
| Primary citation | Iiams, V.,Desai, B.J.,Fedorov, A.A.,Fedorov, E.V.,Almo, S.C.,Gerlt, J.A. Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: importance of residues in the orotate binding site. Biochemistry, 50:8497-8507, 2011 Cited by PubMed: 21870810DOI: 10.1021/bi2012355 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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