3LV6
Crystal structure of the mutant I218F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Summary for 3LV6
| Entry DOI | 10.2210/pdb3lv6/pdb |
| Related | 3LHW 3LTP 3LTS 3LTY 3LV5 |
| Descriptor | Orotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE (3 entities in total) |
| Functional Keywords | mutant i218f, bmp, decarboxylase, lyase, pyrimidine biosynthesis |
| Biological source | Methanothermobacter thermautotrophicus |
| Total number of polymer chains | 2 |
| Total formula weight | 50517.79 |
| Authors | Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (deposition date: 2010-02-19, release date: 2010-06-16, Last modification date: 2023-09-06) |
| Primary citation | Wood, B.M.,Amyes, T.L.,Fedorov, A.A.,Fedorov, E.V.,Shabila, A.,Almo, S.C.,Richard, J.P.,Gerlt, J.A. Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation. Biochemistry, 49:3514-3516, 2010 Cited by PubMed: 20369850DOI: 10.1021/bi100443a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.451 Å) |
Structure validation
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