3NQ6

Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP

Summary for 3NQ6

• Entry DOI: 10.2210/pdb3nq6/pdb
• Related: 3G18 3NQ6 3NQ7 3NQA 3NQC 3NQD 3NQE 3NQF 3NQG 3NQM
• Descriptor: Orotidine 5'-phosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: orotidine 5'-monophosphate decarboxylase, methanobacterium thermoautotrophicum, inhibitor 6-azaump, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Methanothermobacter thermautotrophicus
• Total number of polymer chains: 2
• Total formula weight: 50459.75

Authors

Fedorov, A.A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C. (deposition date: 2010-06-29, release date: 2011-05-11, Last modification date: 2024-03-20)

• Primary citation: A Fedorov, A.,Fedorov, E.V.,Wood, B.M.,Gerlt, J.A.,Almo, S.C.; Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP; To be Published,

Experimental method

X-RAY DIFFRACTION (1.494 Å)