3SY5

Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP

Summary for 3SY5

• Entry DOI: 10.2210/pdb3sy5/pdb
• Related: 3G1A
• Descriptor: Orotidine 5'-phosphate decarboxylase, 6-AZA URIDINE 5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: tim barrel, 6azaump, lyase-inhibitor complex, lyase/inhibitor
• Biological source: Methanothermobacter thermautotrophicus str. Delta H
• Total number of polymer chains: 2
• Total formula weight: 50387.73

Authors

Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Iiams, V.,Gerlt, J.A.,Almo, S.C. (deposition date: 2011-07-15, release date: 2011-09-21, Last modification date: 2023-09-13)

• Primary citation: Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Iiams, V.,Gerlt, J.A.,Almo, S.C.; Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP; To be Published,

Experimental method

X-RAY DIFFRACTION (1.321 Å)