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2Y1N

Structure of c-Cbl-ZAP-70 peptide complex

Summary for 2Y1N
Entry DOI10.2210/pdb2y1n/pdb
Related1B47 1FBV 1M61 1U59 1YVH 2CBL 2Y1M 4A49 4A4B 4A4C
DescriptorE3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, SYK-RELATED TYROSINE KINASE, ZINC ION, ... (5 entities in total)
Functional Keywordsligase-transferase complex, ubiquitin ring e3 ligase, ligase/transferase
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationCytoplasm: P22681 P43403
Total number of polymer chains4
Total formula weight92887.73
Authors
Dou, H.,Sibbet, G.J.,Huang, D.T. (deposition date: 2010-12-08, release date: 2012-01-18, Last modification date: 2023-12-20)
Primary citationDou, H.,Buetow, L.,Hock, A.,Sibbet, G.J.,Vousden, K.H.,Huang, D.T.
Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19:184-, 2012
Cited by
PubMed: 22266821
DOI: 10.1038/NSMB.2231
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.999 Å)
Structure validation

217705

數據於2024-03-27公開中

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