2WQE
Structure of S155R Aurora-A somatic mutant
Summary for 2WQE
Entry DOI | 10.2210/pdb2wqe/pdb |
Related | 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2J4Z 2J50 2W1C 2W1D 2W1E 2W1F 2W1G |
Descriptor | SERINE/THREONINE-PROTEIN KINASE 6, ADENOSINE-5'-DIPHOSPHATE (3 entities in total) |
Functional Keywords | polymorphism, phosphoprotein, nucleotide-binding, cell cycle, transferase |
Biological source | HOMO SAPIENS |
Cellular location | Cytoplasm, cytoskeleton, centrosome: O14965 |
Total number of polymer chains | 1 |
Total formula weight | 31788.67 |
Authors | Bibby, R.,Bayliss, R. (deposition date: 2009-08-20, release date: 2009-09-29, Last modification date: 2023-12-20) |
Primary citation | Bibby, R.A.,Tang, C.,Faisal, A.,Drosopoulos, K.,Lubbe, S.,Houlston, R.,Bayliss, R.,Linardopoulos, S. A Cancer Associated Aurora-A Mutant is Mislocalised and Misregulated due to Loss of Interaction with Tpx2. J.Biol.Chem., 284:33177-, 2009 Cited by PubMed: 19801554DOI: 10.1074/JBC.M109.032722 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report