1OL6

Structure of unphosphorylated D274N mutant of Aurora-A

Summary for 1OL6

Related1MUO 1OL5 1OL7
DescriptorSERINE/THREONINE KINASE 6, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywordstransferase, cell cycle, serine/threonine-protein kinase, atp-binding, phosphorylation
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome O14965
Total number of polymer chains1
Total molecular weight33195.65
Authors
Bayliss, R.,Conti, E. (deposition date: 2003-08-06, release date: 2003-10-30, Last modification date: 2014-09-10)
Primary citation
Bayliss, R.,Sardon, T.,Vernos, I.,Conti, E.
Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle.
Mol.Cell, 12:851-, 2003
PubMed: 14580337 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(03)00392-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.291172.1%7.9%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution