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1OL6

Structure of unphosphorylated D274N mutant of Aurora-A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASERINE/THREONINE KINASE 6polymer28232688.51UniProt (O14965)
Pfam (PF00069)
In PDB
HOMO SAPIENS (HUMAN)SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, AURORA-A, BREAST-TUMOR-AMPLIFIED KINASE
2AADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
3waterwater18.03Chemie (HOH)
Sequence modifications
A: 122 - 403 (UniProt: O14965)
PDBExternal DatabaseDetails
Asn 274Asp 274engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32688.5
Non-Polymers*Number of molecules1
Total formula weight507.2
All*Total formula weight33195.7
*Water molecules are not included.

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