1OL6
Structure of unphosphorylated D274N mutant of Aurora-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE KINASE 6 | polymer | 282 | 32688.5 | 1 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, AURORA-A, BREAST-TUMOR-AMPLIFIED KINASE |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 122 - 403 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Asn 274 | Asp 274 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32688.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 507.2 | |
| All* | Total formula weight | 33195.7 |
