1OL5

Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43

Summary for 1OL5

Related1MUO 1OL6 1OL7
DescriptorSERINE/THREONINE KINASE 6, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywordstransferase-cell cycle complex, cell cycle, transferase, serine/threonine-protein kinase, atp-binding, phosphorylation, transferase/cell cycle
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm, cytoskeleton, centrosome O14965
Nucleus Q9ULW0
Total number of polymer chains2
Total molecular weight38548.83
Authors
Bayliss, R.,Conti, E. (deposition date: 2003-08-06, release date: 2003-10-30, Last modification date: 2011-07-13)
Primary citation
Bayliss, R.,Sardon, T.,Vernos, I.,Conti, E.
Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12:851-, 2003
PubMed: 14580337 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(03)00392-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2481103.5%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1ol5
no rotation
Molmil generated image of 1ol5
rotated about x axis by 90°
Molmil generated image of 1ol5
rotated about y axis by 90°