1OL5
Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE KINASE 6 | polymer | 282 | 32849.4 | 1 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | AURORA-A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, BREAST-TUMOR-AMPLIFIED KINASE |
| 2 | B (B) | RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100 | polymer | 43 | 4911.1 | 1 | UniProt (Q9ULW0) Pfam (PF09041) | HOMO SAPIENS (HUMAN) | TPX2, PROTEIN FLS353, DIL-2, P100, TARGETING PROTEIN FOR XKLP2, HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 519 |
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D, E, I (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37760.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 788.3 | |
| All* | Total formula weight | 38548.8 |
