1MUO

CRYSTAL STRUCTURE OF AURORA-2, AN ONCOGENIC SERINE-THREONINE KINASE

Summary for 1MUO

DescriptorAurora-related kinase 1, ADENOSINE (2 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, centrosome O14965
Total number of polymer chains1
Total molecular weight34699.48
Authors
Cheetham, G.M.T.,Knegtel, R.M.A.,Coll, J.T.,Renwick, S.B.,Swenson, L.,Weber, P.,Lippke, J.A.,Austen, D.A. (deposition date: 2002-09-24, release date: 2003-04-15, Last modification date: 2011-07-13)
Primary citation
Cheetham, G.M.T.,Knegtel, R.M.A.,Coll, J.T.,Renwick, S.B.,Swenson, L.,Weber, P.,Lippke, J.A.,Austen, D.A.
Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase
J.Biol.Chem., 277:42419-42422, 2002
PubMed: 12237287 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.C200426200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers7713.0%15.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution