2WQE
Structure of S155R Aurora-A somatic mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE 6 | polymer | 262 | 30507.1 | 1 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS | AURORA KINASE A, SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE, AURORA-A, AURORA-RELATED KINASE 1, HARK1 |
| 2 | B, C, D (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 3 | E (A) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 127 - 388 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Arg 155 | Ser 155 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30507.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1281.6 | |
| All* | Total formula weight | 31788.7 |
