1MQ4

Crystal Structure of Aurora-A Protein Kinase

Summary for 1MQ4

Related1MP8 1MQB
DescriptorAURORA-RELATED KINASE 1, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordsprotein kinase structure, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, centrosome O14965
Total number of polymer chains1
Total molecular weight32010.93
Authors
Nowakowski, J.,Cronin, C.N.,McRee, D.E.,Knuth, M.W.,Nelson, C.,Pavletich, N.P.,Rodgers, J.,Sang, B.-C.,Scheibe, D.N.,Swanson, R.V.,Thompson, D.A. (deposition date: 2002-09-13, release date: 2003-09-16, Last modification date: 2011-07-13)
Primary citation
Nowakowski, J.,Cronin, C.N.,McRee, D.E.,Knuth, M.W.,Nelson, C.,Pavletich, N.P.,Rodgers, J.,Sang, B.-C.,Scheibe, D.N.,Swanson, R.V.,Thompson, D.A.
Structures of the Cancer-Related Aurora-A, FAK and EphA2 Protein Kinases from Nanovolume Crystallography
Structure, 10:1659-1667, 2002
PubMed: 12467573 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(02)00907-3
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers70.4%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1mq4
no rotation
Molmil generated image of 1mq4
rotated about x axis by 90°
Molmil generated image of 1mq4
rotated about y axis by 90°