2W9B

Binary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA

2W9B の概要

• エントリーDOI: 10.2210/pdb2w9b/pdb
• 関連するPDBエントリー: 1JX4 1JXL 1N48 1N56 1RYR 1RYS 1S0M 1S0N 1S0O 1S10 1S97 1S9F 2AGO 2AGP 2AGQ 2ASD 2ASJ 2ASL 2ATL 2AU0 2BQ3 2BQR 2BQU 2BR0 2C22 2C28 2C2D 2C2E 2C2R 2J6S 2J6T 2J6U 2JEF 2JEG 2JEI 2JEJ 2UVR 2UVU 2UVV 2UVW 2V4Q 2V4R 2V4S 2V4T 2V9W 2VA2 2VA3 2W8K 2W8L 2W9A 2W9C
• 分子名称: DNA POLYMERASE IV, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOCP)-3', 5'-D(*TP*CP*AP*TP*M2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... (6 entities in total)
• 機能のキーワード: dna-directed dna polymerase, n2-dimethyl-g, metal-binding, mutator protein, dna damage, dna repair, dna-binding, transferase, dna replication, nucleotidyltransferase, transferase/dna, dna, dpo4, adduct, cytoplasm, magnesium, polymerase, transferase-dna complex
• 由来する生物種: SULFOLOBUS SOLFATARICUS; 詳細
• 細胞内の位置: Cytoplasm (Probable): Q97W02 2W9B
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 101869.54

構造登録者

Eoff, R.L.,Zhang, H.,Kosekov, I.D.,Rizzo, C.J.,Egli, M.,Guengerich, F.P. (登録日: 2009-01-22, 公開日: 2009-05-12, 最終更新日: 2023-12-13)

• 主引用文献: Zhang, H.,Eoff, R.L.,Kosekov, I.D.,Rizzo, C.J.,Egli, M.,Guengerich, F.P.; Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes.; J.Biol.Chem., 284:17687-, 2009; PubMed: 19542237; DOI: 10.1074/JBC.M109014274

実験手法

X-RAY DIFFRACTION (2.28 Å)