2C4F
crystal structure of factor VII.stf complexed with pd0297121
Summary for 2C4F
Entry DOI | 10.2210/pdb2c4f/pdb |
Related | 1AHW 1BF9 1BOY 1CVW 1DAN 1DVA 1F7E 1F7M 1FAK 1FF7 1FFM 1J9C 1JBU 1JPS 1KLI 1KLJ 1NL8 1O5D 1QFK 1TFH 1UJ3 1W0Y 1W2K 1W7X 1W8B 1WQV 1YGC 1Z6J 2BZ6 2HFT |
Descriptor | COAGULATION FACTOR VII PRECURSOR, TISSUE FACTOR PRECURSOR, CALCIUM ION, ... (10 entities in total) |
Functional Keywords | blood coagulation, serine protease, egf, egf-like domain, gla, receptor enzyme, glycoprotein, hydrolase, protease, hydroxylation, lipoprotein, palmitate, transmembrane |
Biological source | HOMO SAPIENS More |
Total number of polymer chains | 4 |
Total formula weight | 67883.25 |
Authors | Kohrt, J.T.,Zhang, E. (deposition date: 2005-10-18, release date: 2006-10-18, Last modification date: 2020-07-29) |
Primary citation | Kohrt, J.T.,Filipski, K.J.,Cody, W.L.,Cai, C.,Dudley, D.A.,Huis, C.A.V.,Willardsen, J.A.,Narasimhan, L.S.,Zhang, E.,Rapundalo, S.T.,Saiya-Cork, K.,Leadley, R.J.,Edmunds, J.J. The Discovery of Fluoropyridine-Based Inhibitors of the Factor Viia/Tf Complex--Part 2 Bioorg.Med.Chem.Lett., 16:1060-, 2006 Cited by PubMed: 16289811DOI: 10.1016/J.BMCL.2005.10.076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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