1W2K

tf7a_4380 complex

Summary for 1W2K

Entry DOI	10.2210/pdb1w2k/pdb
Related	1AHW 1BF9 1BOY 1CVW 1DAN 1DVA 1F7E 1F7M 1FAK 1FF7 1FFM 1JBU 1JPS 1KLI 1KLJ 1QFK 1TFH 1W0Y 2HFT
Descriptor	BLOOD COAGULATION FACTOR VIIA, TISSUE FACTOR, (2R)-2-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO)-N-BENZYL-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE, ... (9 entities in total)
Functional Keywords	serine protease, hydrolase, blood coagulation, glycoprotein, plasma, vitamin k, calcium-binding, gamma-carboxyglutamic acid, co-factor, coagulation, enzyme complex
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	3
Total formula weight	69442.90
Authors	Banner, D.W.,D'Arcy, A.,Groebke-Zbinden, K.,Ackermann, J.,Kirchhofer, D.,Ji, Y.-H.,Tschopp, T.B.,Wallbaum, S.,Weber, L. (deposition date: 2004-07-06, release date: 2005-06-20, Last modification date: 2023-12-13)
Primary citation	Groebke-Zbinden, K.,Banner, D.W.,Ackermann, J.,D'Arcy, A.,Kirchhofer, D.,Ji, Y.-H.,Tschopp, T.B.,Wallbaum, S.,Weber, L. Design of Selective Phenylglycine Amide Tissue Factor/Factor Viia Inhibitors Bioorg.Med.Chem.Lett., 15:817-, 2005 Cited by PubMed: 15664864 DOI: 10.1016/J.BMCL.2004.10.092 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation