1JPS
Crystal structure of tissue factor in complex with humanized Fab D3h44
Summary for 1JPS
Entry DOI | 10.2210/pdb1jps/pdb |
Related | 1JPT 2HFT |
Descriptor | immunoglobulin Fab D3H44, light chain, immunoglobulin Fab D3H44, heavy chain, tissue factor, ... (4 entities in total) |
Functional Keywords | antigen-antibody recognition, humanized antibody, blood coagulation, interface water molecules, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform 1: Membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P13726 |
Total number of polymer chains | 3 |
Total formula weight | 72393.42 |
Authors | Faelber, K.,Kirchhofer, D.,Presta, L.,Kelley, R.F.,Muller, Y.A. (deposition date: 2001-08-03, release date: 2002-02-03, Last modification date: 2023-10-25) |
Primary citation | Faelber, K.,Kirchhofer, D.,Presta, L.,Kelley, R.F.,Muller, Y.A. The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites. J.Mol.Biol., 313:83-97, 2001 Cited by PubMed: 11601848DOI: 10.1006/jmbi.2001.5036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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