Summary for 1Z6J
|Descriptor||Coagulation factor VII, Tissue factor, CALCIUM ION, ... (7 entities in total)|
|Functional Keywords||blood coagulation, serine protease, thrombosis, gla, pyrazinone, benzamidine, tissue factor, cofactor, enzyme inhibitor complex, hydrolase|
|Biological source||Homo sapiens (human)|
|Total number of polymer chains||3|
|Total molecular weight||69040.68|
Schweitzer, B.A.,Neumann, W.L.,Rahman, H.K.,Kusturin, C.L.,Sample, K.R.,Poda, G.I.,Kurumbail, R.G.,Stevens, A.M.,Stegeman, R.A.,Stallings, W.C.,South, M.S.
Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa.
Bioorg.Med.Chem.Lett., 15:3006-3011, 2005
PubMed: 15913999 (PDB entries with the same primary citation)
Import into Mendeley
X-RAY DIFFRACTION (2 Å)