1GY3

pCDK2/cyclin A in complex with MgADP, nitrate and peptide substrate

1GY3 の概要

• エントリーDOI: 10.2210/pdb1gy3/pdb
• 関連するPDBエントリー: 1AQ1 1B38 1B39 1BUH 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1F5Q 1FIN 1FQ1 1FVT 1FVV 1G5S 1GIH 1GII 1GIJ 1HCK 1HCL 1JST 1JSU 1JSV 1JVP 1QMZ
• 分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, SUBSTRATE PEPTIDE, ... (8 entities in total)
• 機能のキーワード: transferase-transferase substrate complex, cell cycle regulatory protein kinase, thr160-phospho-cyclin dependent protein kinase 2 in association with cyclin a, transferase- transferase substrate complex, transferase/transferase substrate
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 130578.76

構造登録者

Cook, A.,Lowe, E.D.,Chrysina, E.D.,Skamnaki, V.T.,Oikonomakos, N.G.,Johnson, L.N. (登録日: 2002-04-19, 公開日: 2002-04-29, 最終更新日: 2023-12-13)

• 主引用文献: Cook, A.,Lowe, E.D.,Chrysina, E.D.,Skamnaki, V.T.,Oikonomakos, N.G.,Johnson, L.N.; Structural Studies on Phospho-Cdk2/Cyclin a Bound to Nitrate, a Transition State Analogue: Implications for the Protein Kinase Mechanism; Biochemistry, 41:7301-, 2002; PubMed: 12044161; DOI: 10.1021/BI0201724

実験手法

X-RAY DIFFRACTION (2.7 Å)