3RF9
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X-RAY STRUCTURE OF RLMN FROM ESCHERICHIA COLI
Descriptor:Ribosomal RNA large subunit methyltransferase N, IRON/SULFUR CLUSTER, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Boal, A.K., Grove, T.L., McLaughlin, M.I., Yennawar, N., Booker, S.J., Rosenzweig, A.C.
Deposit date:2011-04-05
Release date:2011-05-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
3RFA
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X-RAY STRUCTURE OF RLMN FROM ESCHERICHIA COLI IN COMPLEX WITH S-ADENOSYLMETHIONINE
Descriptor:Ribosomal RNA large subunit methyltransferase N, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE
Authors:Boal, A.K., Grove, T.L., McLaughlin, M.I., Yennawar, N., Booker, S.J., Rosenzweig, A.C.
Deposit date:2011-04-05
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for methyl transfer by a radical SAM enzyme.
Science, 332, 2011
3T7V
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CRYSTAL STRUCTURE OF METHYLORNITHINE SYNTHASE (PYLB)
Descriptor:methylornithine synthase PylB, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ...
Authors:Quitterer, F., List, A., Eisenreich, W., Bacher, A., Groll, M.
Deposit date:2011-07-31
Release date:2011-11-30
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of methylornithine synthase (PylB): insights into the pyrrolysine biosynthesis.
Angew.Chem.Int.Ed.Engl., 51, 2012
4U0O
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CRYSTAL STRUCTURE OF THERMOSYNECHOCOCCUS ELONGATUS LIPOYL SYNTHASE 2 COMPLEXED WITH MTA AND DTT
Descriptor:Lipoyl synthase 2, IRON/SULFUR CLUSTER, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
Authors:Harmer, J.E., Hiscox, M.J., Dinis, P.C., Sandy, J., Roach, P.L.
Deposit date:2014-07-13
Release date:2014-08-20
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions.
Biochem.J., 464, 2014
4U0P
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THE CRYSTAL STRUCTURE OF LIPOYL SYNTHASE IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE
Descriptor:Lipoyl synthase 2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Harmer, J.E., Hiscox, M.J., Sandy, J., Dinis, P.C., Roach, P.L.
Deposit date:2014-07-13
Release date:2014-08-20
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.623 Å)
Cite:Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions.
Biochem.J., 464, 2014
5HR6
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X-RAY CRYSTAL STRUCTURE OF C118A RLMN WITH CROSS-LINKED TRNA PURIFIED FROM ESCHERICHIA COLI
Descriptor:RlmN methylase, tRNA Glu, METHIONINE, ...
Authors:Schwalm, E.L., Grove, T.L., Booker, S.J., Boal, A.K.
Deposit date:2016-01-22
Release date:2016-04-13
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Science, 352, 2016
5HR7
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X-RAY CRYSTAL STRUCTURE OF C118A RLMN FROM ESCHERICHIA COLI WITH CROSS-LINKED IN VITRO TRANSCRIBED TRNA
Descriptor:tRNA Glu, Dual-specificity RNA methyltransferase RlmN, MAGNESIUM ION, ...
Authors:Schwalm, E.L., Grove, T.L., Booker, S.J., Boal, A.K.
Deposit date:2016-01-22
Release date:2016-04-13
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.
Science, 352, 2016
6FD2
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RADICAL SAM 1,2-DIOL DEHYDRATASE APRD4 IN COMPLEX WITH ITS SUBSTRATE PAROMAMINE
Descriptor:Putative apramycin biosynthetic oxidoreductase 4, paromamine, IRON/SULFUR CLUSTER, ...
Authors:Liu, W.Q., Amara, P., Mouesca, J.M., Ji, X., Renoux, O., Martin, L., Zhang, C., Zhang, Q., Nicolet, Y.
Deposit date:2017-12-21
Release date:2018-01-17
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J. Am. Chem. Soc., 140, 2018
1OLT
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COPROPORPHYRINOGEN III OXIDASE (HEMN) FROM ESCHERICHIA COLI IS A RADICAL SAM ENZYME.
Descriptor:OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE
Authors:Layer, G., Moser, J., Heinz, D.W., Jahn, D., Schubert, W.-D.
Deposit date:2003-08-13
Release date:2003-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes
Embo J., 22, 2003
1R30
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THE CRYSTAL STRUCTURE OF BIOTIN SYNTHASE, AN S-ADENOSYLMETHIONINE-DEPENDENT RADICAL ENZYME
Descriptor:Biotin synthase, S-ADENOSYLMETHIONINE, IRON/SULFUR CLUSTER, ...
Authors:Berkovitch, F., Nicolet, Y., Wan, J.T., Jarrett, J.T., Drennan, C.L.
Deposit date:2003-09-30
Release date:2004-01-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme.
Science, 303, 2004
1TV7
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STRUCTURE OF THE S-ADENOSYLMETHIONINE DEPENDENT ENZYME MOAA
Descriptor:Molybdenum cofactor biosynthesis protein A, SULFATE ION, IRON/SULFUR CLUSTER
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2004-06-28
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TV8
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STRUCTURE OF MOAA IN COMPLEX WITH S-ADENOSYLMETHIONINE
Descriptor:Molybdenum cofactor biosynthesis protein A, SULFATE ION, S-ADENOSYLMETHIONINE, ...
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2004-06-28
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2A5H
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2.1 ANGSTROM X-RAY CRYSTAL STRUCTURE OF LYSINE-2,3-AMINOMUTASE FROM CLOSTRIDIUM SUBTERMINALE SB4, WITH MICHAELIS ANALOG (L-ALPHA-LYSINE EXTERNAL ALDIMINE FORM OF PYRIDOXAL-5'-PHOSPHATE).
Descriptor:L-lysine 2,3-aminomutase, ZINC ION, SULFATE ION, ...
Authors:Lepore, B.W., Ruzicka, F.J., Frey, P.A., Ringe, D.
Deposit date:2005-06-30
Release date:2005-10-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The X-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2FB2
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STRUCTURE OF THE MOAA ARG17/266/268/ALA TRIPLE MUTANT
Descriptor:Molybdenum cofactor biosynthesis protein A, SULFATE ION, S-ADENOSYLMETHIONINE, ...
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2005-12-08
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism
Proc.Natl.Acad.Sci.USA, 103, 2006
2FB3
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STRUCTURE OF MOAA IN COMPLEX WITH 5'-GTP
Descriptor:Molybdenum cofactor biosynthesis protein A, SULFATE ION, METHIONINE, ...
Authors:Haenzelmann, P., Schindelin, H.
Deposit date:2005-12-08
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism
Proc.Natl.Acad.Sci.USA, 103, 2006
2QGQ
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CRYSTAL STRUCTURE OF TM_1862 FROM THERMOTOGA MARITIMA. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET VR77
Descriptor:Protein TM_1862, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID
Authors:Forouhar, F., Neely, H., Hussain, M., Seetharaman, J., Fang, Y., Chen, C.X., Cunningham, K., Conover, K., Ma, L.-C., Xiao, R., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-29
Release date:2007-07-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Post-translational Modification of Ribosomal Proteins: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF RimO FROM THERMOTOGA MARITIMA, A RADICAL S-ADENOSYLMETHIONINE METHYLTHIOTRANSFERASE.
J.Biol.Chem., 285, 2010
2YX0
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CRYSTAL STRUCTURE OF P. HORIKOSHII TYW1
Descriptor:radical sam enzyme
Authors:Goto-Ito, S., Ishii, R., Ito, T., Shibata, R., Fusatomi, E., Sekine, S., Bessho, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-23
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis
Acta Crystallogr.,Sect.D, 63, 2007
2Z2U
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CRYSTAL STRUCTURE OF ARCHAEAL TYW1
Descriptor:UPF0026 protein MJ0257
Authors:Suzuki, Y., Ishitani, R., Nureki, O.
Deposit date:2007-05-28
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Radical SAM Enzyme Catalyzing Tricyclic Modified Base Formation in tRNA
J.Mol.Biol., 372, 2007
3C8F
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4FE-4S-PYRUVATE FORMATE-LYASE ACTIVATING ENZYME WITH PARTIALLY DISORDERED ADOMET
Descriptor:Pyruvate formate-lyase 1-activating enzyme, IRON/SULFUR CLUSTER, [(3S)-3-amino-3-carboxypropyl](ethyl)methylsulfonium, ...
Authors:Vey, J.L., Drennan, C.L.
Deposit date:2008-02-11
Release date:2008-10-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CB8
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4FE-4S-PYRUVATE FORMATE-LYASE ACTIVATING ENZYME IN COMPLEX WITH ADOMET AND A PEPTIDE SUBSTRATE
Descriptor:Pyruvate formate-lyase 1-activating enzyme, peptide substrate VSGYAV, SODIUM ION, ...
Authors:Vey, J.L., Drennan, C.L.
Deposit date:2008-02-21
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CIW
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X-RAY STRUCTURE OF THE [FEFE]-HYDROGENASE MATURASE HYDE FROM THERMOTOGA MARITIMA
Descriptor:FeFe-Hydrogenase maturase, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
Authors:Nicolet, Y., Ruback, J.K., Posewitz, M.C., Amara, P., Mathevon, C., Atta, M., Fontecave, M., Fontecilla-Camps, J.C.
Deposit date:2008-03-12
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
3CIX
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X-RAY STRUCTURE OF THE [FEFE]-HYDROGENASE MATURASE HYDE FROM THERMOTOGA MARITIMA IN COMPLEX WITH THIOCYANATE
Descriptor:FeFe-Hydrogenase maturase, THIOCYANATE ION, CHLORIDE ION, ...
Authors:Nicolet, Y., Ruback, J.K., Posewitz, M.C., Amara, P., Mathevon, C., Atta, M., Fontecave, M., Fontecilla-Camps, J.C.
Deposit date:2008-03-12
Release date:2008-04-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray Structure of the [FeFe]-Hydrogenase Maturase HydE from Thermotoga maritima
J.Biol.Chem., 283, 2008
3IIX
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X-RAY STRUCTURE OF THE FEFE-HYDROGENASE MATURASE HYDE FROM T. MARITIMA IN COMPLEX WITH METHIONINE AND 5'DEOXYADENOSINE
Descriptor:Biotin synthetase, putative, IRON/SULFUR CLUSTER, ...
Authors:Nicolet, Y., Amara, P., Mouesca, J.M., Fontecilla-Camps, J.C.
Deposit date:2009-08-03
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
3IIZ
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X-RAY STRUCTURE OF THE FEFE-HYDROGENASE MATURASE HYDE FROM T. MARITIMA IN COMPLEX WITH S-ADENOSYL-L-METHIONINE
Descriptor:Biotin synthetase, putative, IRON/SULFUR CLUSTER, ...
Authors:Nicolet, Y., Amara, P., Mouesca, J.M., Fontecilla-Camps, J.C.
Deposit date:2009-08-03
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Unexpected electron transfer mechanism upon AdoMet cleavage in radical SAM proteins
Proc.Natl.Acad.Sci.USA, 2009
4JXC
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X-RAY SNAPSHOTS OF POSSIBLE INTERMEDIATES IN THE TIME COURSE OF SYNTHESIS AND DEGRADATION OF PROTEIN-BOUND FE4S4 CLUSTERS
Descriptor:FEFE-HYDROGENASE MATURASE, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ...
Authors:Nicolet, Y., Rohac, R., Martin, L., Fontecilla-Camps, J.C.
Deposit date:2013-03-28
Release date:2013-05-01
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.
Proc.Natl.Acad.Sci.USA, 110, 2013
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