Crystal structure of Thermosynechococcus elongatus Lipoyl Synthase 2 complexed with MTA and DTT

Summary for 4U0O

DescriptorLipoyl synthase 2, IRON/SULFUR CLUSTER, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (5 entities in total)
Functional Keywordsradical sam, tim barrel, sulfotransferase, transferase
Biological sourceThermosynechococcus elongatus
Cellular locationCytoplasm  Q8DLC2
Total number of polymer chains1
Total molecular weight33760.22
Harmer, J.E.,Hiscox, M.J.,Dinis, P.C.,Sandy, J.,Roach, P.L. (deposition date: 2014-07-13, release date: 2014-08-20, Last modification date: 2017-08-30)
Primary citation
Harmer, J.E.,Hiscox, M.J.,Dinis, P.C.,Fox, S.J.,Iliopoulos, A.,Hussey, J.E.,Sandy, J.,Van Beek, F.T.,Essex, J.W.,Roach, P.L.
Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions.
Biochem.J., 464:123-133, 2014
PubMed: 25100160 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20140895
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24221.1%2.3%3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report