4U0O
Crystal structure of Thermosynechococcus elongatus Lipoyl Synthase 2 complexed with MTA and DTT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009107 | biological_process | lipoate biosynthetic process |
| B | 0009249 | biological_process | protein lipoylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016992 | molecular_function | lipoate synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SF4 B 301 |
| Chain | Residue |
| B | CYS63 |
| B | CYS67 |
| B | PHE69 |
| B | CYS70 |
| B | DTT303 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 B 302 |
| Chain | Residue |
| B | THR55 |
| B | SER283 |
| B | CYS37 |
| B | CYS42 |
| B | ASN44 |
| B | CYS48 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DTT B 303 |
| Chain | Residue |
| B | ILE36 |
| B | THR104 |
| B | SER105 |
| B | SF4301 |
| B | MTA304 |
| B | HOH450 |
| B | HOH505 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue MTA B 304 |
| Chain | Residue |
| B | PHE69 |
| B | ASN169 |
| B | GLU171 |
| B | MET210 |
| B | GLN239 |
| B | LEU241 |
| B | ARG281 |
| B | SER283 |
| B | DTT303 |
| B | HOH490 |
| B | HOH483 |
| B | HOH484 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00206, ECO:0000269|PubMed:25100160, ECO:0007744|PDB:4U0O, ECO:0007744|PDB:4U0P |
| Chain | Residue | Details |
| B | CYS37 | |
| B | CYS42 | |
| B | CYS48 | |
| B | CYS63 | |
| B | CYS67 | |
| B | CYS70 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00206, ECO:0000269|PubMed:25100160, ECO:0007744|PDB:4U0O |
| Chain | Residue | Details |
| B | SER283 |
