3TJZ
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CRYSTAL STRUCTURE OF ARF1 BOUND TO THE GAMMA/ZETA-COP CORE COMPLEX
Descriptor:ADP-ribosylation factor 1, Coatomer subunit gamma, Coatomer subunit zeta-1, ...
Authors:Goldberg, J., Yu, X., Breitman, M.
Deposit date:2011-08-25
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structure-based mechanism for arf1-dependent recruitment of coatomer to membranes.
Cell(Cambridge,Mass.), 148, 2012
4NEE
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CRYSTAL STRUCTURE OF AP-2 ALPHA/SIMGA2 COMPLEX BOUND TO HIV-1 NEF
Descriptor:AP-2 complex subunit sigma, AP-2 complex subunit alpha-2, Protein Nef
Authors:Hurley, J.H., Bonifacino, J.S., Ren, X., Park, S.Y.
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.8841 Å)
Cite:How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
5MU7
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CRYSTAL STRUCTURE OF THE BETA/DELTA-COPI CORE COMPLEX
Descriptor:Coatomer subunit beta, Coatomer subunit delta-like protein
Authors:Kopp, J., Aderhold, P., Wieland, F., Sinning, I.
Deposit date:2017-01-12
Release date:2017-06-28
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
1W63
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AP1 CLATHRIN ADAPTOR CORE
Descriptor:ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTOR-RELATED PROTEIN COMPLEX 1, ...
Authors:Heldwein, E., Macia, E., Wang, J., Yin, H.L., Kirchhausen, T., Harrison, S.C.
Deposit date:2004-08-12
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
2BP5
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Descriptor:CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4
Authors:Royle, S.J., Evans, P.R., Owen, D.J., Murrell-Lagnado, R.D.
Deposit date:2005-04-18
Release date:2005-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
2JKR
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AP2 CLATHRIN ADAPTOR CORE WITH DILEUCINE PEPTIDE RM(PHOSPHOS)QIKRLLSE
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKT
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AP2 CLATHRIN ADAPTOR CORE WITH CD4 DILEUCINE PEPTIDE RM(PHOSPHOS) EIKRLLSE Q TO E MUTANT
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT SIGMA-1, ...
Authors:Owen, D.J., McCoy, A.J., Kelly, B.T., Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2VGL
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AP2 CLATHRIN ADAPTOR CORE
Descriptor:ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
Authors:Owen, D.J., Collins, B.M., McCoy, A.J., Evans, P.R.
Deposit date:2007-11-14
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
2XA7
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AP2 CLATHRIN ADAPTOR CORE IN ACTIVE COMPLEX WITH CARGO PEPTIDES
Descriptor:ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
Authors:Jackson, L.P., Kelly, B.T., McCoy, A.J., Evans, P.R., Owen, D.J.
Deposit date:2010-03-29
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
4HMY
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STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1 CLATHRIN ADAPTOR COMPLEX BY ARF1
Descriptor:AP-1 complex subunit gamma-1, AP-1 complex subunit beta-1, AP-1 complex subunit mu-1, ...
Authors:Ren, X., Farias, G.G., Canagarajah, B.J., Bonifacino, J.S., Hurley, J.H.
Deposit date:2012-10-18
Release date:2013-03-06
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
4P6Z
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CRYSTAL STRUCTURE OF THE HUMAN BST2 CYTOPLASMIC DOMAIN AND THE HIV-1 VPU CYTOPLASMIC DOMAIN BOUND TO THE CLATHRIN ADAPTOR PROTEIN COMPLEX 1 (AP1) CORE
Descriptor:AP-1 complex subunit gamma-1, AP-1 complex subunit sigma-1A, AP-1 complex subunit mu-1, ...
Authors:Jia, X., Xiong, Y.
Deposit date:2014-03-25
Release date:2014-05-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.
Elife, 3, 2014
4UQI
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AP2 CONTROLS CLATHRIN POLYMERIZATION WITH A MEMBRANE-ACTIVATED SWITCH
Descriptor:AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ...
Authors:Kelly, B.T., Graham, S.C., Liska, N., Dannhauser, P.N., Hoening, S., Ungewickell, E.J., Owen, D.J.
Deposit date:2014-06-23
Release date:2014-07-30
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
5A1U
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THE STRUCTURE OF THE COPI COAT TRIAD
Descriptor:ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA', ...
Authors:Dodonova, S.O., Diestelkoetter-Bachert, P., von Appen, A., Hagen, W.J.H., Beck, R., Beck, M., Wieland, F., Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1V
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THE STRUCTURE OF THE COPI COAT LINKAGE I
Descriptor:ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA, ...
Authors:Dodonova, S.O., Diestelkoetter-Bachert, P., von Appen, A., Hagen, W.J.H., Beck, R., Beck, M., Wieland, F., Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1W
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THE STRUCTURE OF THE COPI COAT LINKAGE II
Descriptor:ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA', ...
Authors:Dodonova, S.O., Diestelkoetter-Bachert, P., von Appen, A., Hagen, W.J.H., Beck, R., Beck, M., Wieland, F., Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1X
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THE STRUCTURE OF THE COPI COAT LINKAGE III
Descriptor:ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA', ...
Authors:Dodonova, S.O., Diestelkoetter-Bachert, P., von Appen, A., Hagen, W.J.H., Beck, R., Beck, M., Wieland, F., Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5A1Y
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THE STRUCTURE OF THE COPI COAT LINKAGE IV
Descriptor:ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT ALPHA, COATOMER SUBUNIT BETA', ...
Authors:Dodonova, S.O., Diestelkoetter-Bachert, P., von Appen, A., Hagen, W.J.H., Beck, R., Beck, M., Wieland, F., Briggs, J.A.G.
Deposit date:2015-05-06
Release date:2015-07-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (21 Å)
Cite:Vesicular Transport. A Structure of the Copi Coat and the Role of Coat Proteins in Membrane Vesicle Assembly.
Science, 349, 2015
5FPI
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MU2 ADAPTIN SUBUNIT OF THE AP2 ADAPTOR (C-TERMINAL DOMAIN) COMPLEXED WITH INTEGRIN ALPHA4 INTERNALISATION PEPTIDE QYKSILQE
Descriptor:AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J., Evans, P.R., Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016
5NZR
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THE STRUCTURE OF THE COPI COAT LEAF
Descriptor:Coatomer subunit alpha, Coatomer subunit beta, Coatomer subunit beta', ...
Authors:Dodonova, S.O., Aderhold, P., Kopp, J., Ganeva, I., Roehling, S., Hagen, W.J.H., Sinning, I., Wieland, F., Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZS
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THE STRUCTURE OF THE COPI COAT LEAF IN COMPLEX WITH THE ARFGAP2 UNCOATING FACTOR
Descriptor:Coatomer subunit alpha, Coatomer subunit beta, Coatomer subunit beta', ...
Authors:Dodonova, S.O., Aderhold, P., Kopp, J., Ganeva, I., Roehling, S., Hagen, W.J.H., Sinning, I., Wieland, F., Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZT
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THE STRUCTURE OF THE COPI COAT LINKAGE I
Descriptor:Coatomer subunit alpha, Coatomer subunit epsilon, Coatomer subunit beta, ...
Authors:Dodonova, S.O., Aderhold, P., Kopp, J., Ganeva, I., Roehling, S., Hagen, W.J.H., Sinning, I., Wieland, F., Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (17 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZU
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THE STRUCTURE OF THE COPI COAT LINKAGE II
Descriptor:Coatomer subunit alpha, Coatomer subunit beta, Coatomer subunit beta', ...
Authors:Dodonova, S.O., Aderhold, P., Kopp, J., Ganeva, I., Roehling, S., Hagen, W.J.H., Sinning, I., Wieland, F., Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (15 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZV
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THE STRUCTURE OF THE COPI COAT LINKAGE IV
Descriptor:Coatomer subunit alpha, Coatomer subunit epsilon, Coatomer subunit beta, ...
Authors:Dodonova, S.O., Aderhold, P., Kopp, J., Ganeva, I., Roehling, S., Hagen, W.J.H., Sinning, I., Wieland, F., Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (17.299999 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
6CM9
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STRUCTURE OF THE CARGO BOUND AP-1:ARF1:TETHERIN-NEF CLOSED TRIMER MONOMERIC SUBUNIT
Descriptor:Bone marrow stromal antigen 2, Protein Nef chimera, AP-1 complex subunit beta-1, ...
Authors:Morris, K.L., Buffalo, C.Z., Ren, X., Hurley, J.H.
Deposit date:2018-03-03
Release date:2018-08-08
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6CRI
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STRUCTURE OF THE CARGO BOUND AP-1:ARF1:TETHERIN-NEF STABLE CLOSED TRIMER
Descriptor:Bone marrow stromal antigen 2, Protein Nef chimera, AP-1 complex subunit beta-1, ...
Authors:Morris, K.L., Buffalo, C.Z., Hurley, J.H.
Deposit date:2018-03-18
Release date:2018-08-01
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
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