4P6Z
Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 Vpu cytoplasmic domain bound to the clathrin adaptor protein complex 1 (AP1) core
Summary for 4P6Z
Entry DOI | 10.2210/pdb4p6z/pdb |
Descriptor | AP-1 complex subunit gamma-1, AP-1 complex subunit sigma-1A, AP-1 complex subunit mu-1, ... (7 entities in total) |
Functional Keywords | bst2, tetherin, vpu, hiv, clathrin, ap1, antiviral, restriction factor, antagonism, protein transport |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 216053.86 |
Authors | |
Primary citation | Jia, X.,Weber, E.,Tokarev, A.,Lewinski, M.,Rizk, M.,Suarez, M.,Guatelli, J.,Xiong, Y. Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. Elife, 3:e02362-e02362, 2014 Cited by PubMed: 24843023DOI: 10.7554/eLife.02362 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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