6URI

HIV-1 Nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex

Summary for 6URI

• Entry DOI: 10.2210/pdb6uri/pdb
• Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit sigma, Protein Nef, ... (7 entities in total)
• Functional Keywords: cd4, viral protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 6
• Total formula weight: 202043.47

Authors

Jia, X.,Kwon, Y. (deposition date: 2019-10-23, release date: 2020-07-29, Last modification date: 2023-10-11)

• Primary citation: Kwon, Y.,Kaake, R.M.,Echeverria, I.,Suarez, M.,Karimian Shamsabadi, M.,Stoneham, C.,Ramirez, P.W.,Kress, J.,Singh, R.,Sali, A.,Krogan, N.,Guatelli, J.,Jia, X.; Structural basis of CD4 downregulation by HIV-1 Nef.; Nat.Struct.Mol.Biol., 27:822-828, 2020; PubMed: 32719457; DOI: 10.1038/s41594-020-0463-z

Experimental method

X-RAY DIFFRACTION (3 Å)