5FPI

Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE

Summary for 5FPI

DescriptorAP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT (3 entities in total)
Functional Keywordsendocytosis, clathrin adaptor
Biological sourceRATTUS NORVEGICUS (NORWAY RAT)
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Cellular locationCell membrane  P84092
Total number of polymer chains2
Total molecular weight52053.25
Authors
Owen, D.J.,Evans, P.R.,Ivaska, J. (deposition date: 2015-11-30, release date: 2016-01-20, Last modification date: 2016-03-02)
Primary citation
De Franceschi, N.,Arjonen, A.,Elkhatib, N.,Denessiouk, K.,Wrobel, A.G.,Wilson, T.A.,Pouwels, J.,Montagnac, G.,Owen, D.J.,Ivaska, J.
Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23:172-, 2016
PubMed: 26779610 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.3161
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.77 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.2034 0.8% 9.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25