1AK5
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, SULFATE ION
Authors:Whitby, F.G.
Deposit date:1997-05-28
Release date:1997-09-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
Biochemistry, 36, 1997
1B3O
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TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE
Descriptor:PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, ...
Authors:Colby, T.D., Vanderveen, K., Strickler, M.D., Goldstein, B.M.
Deposit date:1998-12-14
Release date:1999-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Proc.Natl.Acad.Sci.USA, 96, 1999
1EEP
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2.4 A RESOLUTION CRYSTAL STRUCTURE OF BORRELIA BURGDORFERI INOSINE 5'-MONPHOSPHATE DEHYDROGENASE IN COMPLEX WITH A SULFATE ION
Descriptor:INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE, SULFATE ION
Authors:McMillan, F.M., Cahoon, M., White, A., Hedstrom, L., Petsko, G.A., Ringe, D.
Deposit date:2000-02-01
Release date:2000-03-29
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
Biochemistry, 39, 2000
1ZFJ
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH; EC 1.1.1.205) FROM STREPTOCOCCUS PYOGENES
Descriptor:INOSINE MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID
Authors:Zhang, R., Evans, G., Rotella, F.J., Westbrook, E.M., Beno, D., Huberman, E., Joachimiak, A., Collart, F.R.
Deposit date:1999-03-29
Release date:2000-03-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase.
Biochemistry, 38, 1999
1JR1
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CRYSTAL STRUCTURE OF INOSINE MONOPHOSPHATE DEHYDROGENASE IN COMPLEX WITH MYCOPHENOLIC ACID
Descriptor:Inosine-5'-Monophosphate Dehydrogenase 2, POTASSIUM ION, INOSINIC ACID, ...
Authors:Sintchak, M.D., Fleming, M.A., Futer, O., Raybuck, S.A., Chambers, S.P., Caron, P.R., Murcko, M.A., Wilson, K.P.
Deposit date:2001-08-09
Release date:2001-09-05
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.
Cell(Cambridge,Mass.), 85, 1996
1ME7
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH RVP AND MOA BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, SODIUM ION, POTASSIUM ION, ...
Authors:Prosise, G.L., Wu, J., Luecke, H.
Deposit date:2002-08-08
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
J.Biol.Chem., 277, 2002
1ME8
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH RVP BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, SODIUM ION, ...
Authors:Prosise, G.L., Wu, J., Luecke, H.
Deposit date:2002-08-08
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
J.Biol.Chem., 277, 2002
1JCN
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BINARY COMPLEX OF HUMAN TYPE-I INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP
Descriptor:INOSINE MONOPHOSPHATE DEHYDROGENASE I, 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE
Authors:Risal, D., Strickler, M.D., Goldstein, B.M.
Deposit date:2001-06-11
Release date:2003-06-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Human Type I Inosine Monophosphate Dehydrogenase and Implications for Isoform Specificity
To be Published
1LRT
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CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, B-OCTYLGLUCOSIDE, POTASSIUM ION, ...
Authors:Gan, L., Petsko, G.A., Hedstrom, L.
Deposit date:2002-05-15
Release date:2003-07-07
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis
Biochemistry, 41, 2003
1PVN
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THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN IMP DEHYDROGENASE CATALYTIC DOMAIN AND A TRANSITION STATE ANALOGUE MZP
Descriptor:Inosine-5'-monophosphate dehydrogenase, POTASSIUM ION, 4-CARBAMOYL-1-BETA-D-RIBOFURANOSYL-IMIDAZOLIUM-5-OLATE-5'-PHOSPHATE, ...
Authors:Gan, L., Seyedsayamdost, M., Shuto, S., Matsuda, A., Petsko, G.A., Hedstrom, L.
Deposit date:2003-06-27
Release date:2003-07-22
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Immunosuppressive Agent Mizoribine Monophosphate Forms a Transition State Analogue Complex with Inosine Monophosphate Dehydrogenase
Biochemistry, 42, 2003
1ME9
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH IMP BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, INOSINIC ACID
Authors:Prosise, G.L., Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEH
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH IMP AND MOA BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, INOSINIC ACID, ...
Authors:Prosise, G.L., Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEI
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH XMP AND MYCOPHENOLIC ACID BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, XANTHOSINE-5'-MONOPHOSPHATE, ...
Authors:Prosise, G.L., Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1MEW
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INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) FROM TRITRICHOMONAS FOETUS WITH XMP AND NAD BOUND
Descriptor:INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, XANTHOSINE-5'-MONOPHOSPHATE, ...
Authors:Prosise, G.L., Luecke, H.
Deposit date:2002-08-08
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326, 2003
1NF7
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TERNARY COMPLEX OF THE HUMAN TYPE II INOSINE MONOPHOSPHATE DEDHYDROGENASE WITH RIBAVIRIN MONOPHOSPHATE AND C2-MYCOPHENOLIC ADENINE DINUCLEOTIDE
Descriptor:Inosine-5'-monophosphate dehydrogenase 2, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
Authors:Risal, D., Strickler, M.D., Goldstein, B.M.
Deposit date:2002-12-13
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Inosine Monophosphate Dehydrogenase type II complexed with the MPA/NAD analog C2-MAD
To be Published
1NFB
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TERNARY COMPLEX OF THE HUMAN TYPE II INOSINE MONOPHOSPHATE DEDHYDROGENASE WITH 6CL-IMP AND NAD
Descriptor:Inosine-5'-monophosphate dehydrogenase 2, 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, ...
Authors:Risal, D., Strickler, M.D., Goldstein, B.M.
Deposit date:2002-12-13
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II
To be Published
2BLE
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STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE GMPR1 IN COMPLEX WITH GMP
Descriptor:GMP REDUCTASE I, GUANOSINE-5'-MONOPHOSPHATE, SODIUM ION
Authors:Bunkoczi, G., Haroniti, A., Ng, S., von Delft, F., Oppermann, U., Arrowsmith, C., Sundstrom, M., Edwards, A., Gileadi, O.
Deposit date:2005-03-03
Release date:2005-03-09
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp
To be Published
1VRD
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CRYSTAL STRUCTURE OF INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (TM1347) FROM THERMOTOGA MARITIMA AT 2.18 A RESOLUTION
Descriptor:inosine-5'-monophosphate dehydrogenase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-02-22
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution
To be published
2BWG
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STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE GMPR1 IN COMPLEX WITH GMP
Descriptor:GMP REDUCTASE I, POTASSIUM ION, GUANOSINE-5'-MONOPHOSPHATE
Authors:Bunkoczi, G., Haroniti, A., Ng, S., von Delft, F., Gileadi, O., Oppermann, U., Arrowsmith, C., Edwards, A., Sundstrom, M.
Deposit date:2005-07-13
Release date:2005-07-20
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Human Guanosine Monophosphate Reductase Gmpr1 in Complex with Gmp
To be Published
2BZN
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CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP
Descriptor:GMP REDUCTASE 2, INOSINIC ACID
Authors:Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J.
Deposit date:2005-08-19
Release date:2005-09-02
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
2C6Q
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CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP AND NADPH
Descriptor:GMP REDUCTASE 2, INOSINIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J., Nordlund, P.
Deposit date:2005-11-11
Release date:2005-11-30
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
2A7R
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CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 (GMPR2)
Descriptor:GMP reductase 2, SULFATE ION, GUANOSINE-5'-MONOPHOSPHATE
Authors:Li, J., Wei, Z., Zheng, M., Gu, X., Deng, Y., Qiu, R., Chen, F., Ji, C., Gong, W., Xie, Y., Mao, Y.
Deposit date:2005-07-05
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP
J.Mol.Biol., 355, 2006
1YPF
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CRYSTAL STRUCTURE OF GUAC (BA5705) FROM BACILLUS ANTHRACIS AT 1.8 A RESOLUTION
Descriptor:GMP reductase
Authors:Grenha, R., Levdikov, V.M., Blagova, E.V., Fogg, M.J., Brannigan, J.A., Wilkinson, A.J., Wilson, K.S., Structural Proteomics in Europe (SPINE)
Deposit date:2005-01-31
Release date:2006-02-14
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution.
To be Published
2CU0
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CRYSTAL STRUCTURE OF INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE FROM PYROCOCCUS HORIKOSHII OT3
Descriptor:Inosine-5'-monophosphate dehydrogenase, XANTHOSINE-5'-MONOPHOSPHATE
Authors:Asada, Y., Kunishima, N., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-24
Release date:2006-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of inosine-5'-monophosphate dehydrogenase from Pyrococcus horikoshii OT3
To be Published
2A1Y
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CRYSTAL STRUCTURE OF GUAC-GMP COMPLEX FROM BACILLUS ANTHRACIS AT 2.26 A RESOLUTION.
Descriptor:GMP reductase, GUANOSINE-5'-MONOPHOSPHATE
Authors:Grenha, R., Levdikov, V.M., Blagova, E.V., Fogg, M.J., Brannigan, J.A., Wilkinson, A.J., Wilson, K.S., Structural Proteomics in Europe (SPINE)
Deposit date:2005-06-21
Release date:2006-07-04
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A resolution.
To be Published
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