1LRT

CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME

Summary for 1LRT

Related1AK5
DescriptorINOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, octyl beta-D-glucopyranoside, POTASSIUM ION, ... (7 entities in total)
Functional Keywordsternary complex, alpha-beta barrel, flexible loop, flap, oxidoreductase
Biological sourceTritrichomonas foetus
Cellular locationCytoplasm  P50097
Total number of polymer chains4
Total molecular weight171065.15
Authors
Gan, L.,Petsko, G.A.,Hedstrom, L. (deposition date: 2002-05-15, release date: 2003-07-07, Last modification date: 2020-07-29)
Primary citation
Gan, L.,Petsko, G.A.,Hedstrom, L.
Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis
Biochemistry, 41:13309-13317, 2003
PubMed: 12403633 (PDB entries with the same primary citation)
DOI: 10.1021/bi0203785
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers14 0.8% 2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02