1LRT
CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE | polymer | 376 | 41198.9 | 4 | UniProt (P50097) Pfam (PF00478) | Tritrichomonas foetus | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, IMP DEHYDROGENASE, IMPDH, IMPD |
| 2 | E, F (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 3 | G, N, T, Y (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | H, O, U, Z (A, B, C, D) | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) | |||
| 5 | AA, I, P, V (D, A, B, C) | BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE | non-polymer | 667.5 | 4 | Chemie (TAD) | |||
| 6 | BA, CA, DA, J, K... (D, A, B, C) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 12 | Chemie (TRS) | |||
| 7 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 543 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 100 (UniProt: P50097)
A, B, C, D: 227 - 503 (UniProt: P50097)
A, B, C, D: 227 - 503 (UniProt: P50097)
| PDB | External Database | Details |
|---|---|---|
| Asp 279 | Glu 279 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164795.6 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 6269.6 | |
| All* | Total formula weight | 171065.2 |
