1LRT

CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE	polymer	376	41198.9	4	UniProt (P50097) Pfam (PF00478) In PDB	Tritrichomonas foetus	INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, IMP DEHYDROGENASE, IMPDH, IMPD
2	A	octyl beta-D-glucopyranoside	non-polymer		292.4	2	Chemie (BOG)
3	A, B, C, D	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)
4	A, B, C, D	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
5	D, A, B, C	BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE	non-polymer		667.5	4	Chemie (TAD)
6	D, A, B, C	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	12	Chemie (TRS)
7		water	water		18.0	543	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 100 (UniProt: P50097)
A, B, C, D: 227 - 503 (UniProt: P50097)

PDB	External Database	Details
Asp 279	Glu 279	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164795.6
Non-Polymers*	Number of molecules	26
	Total formula weight	6269.6
All*	Total formula weight	171065.2

*Water molecules are not included.