1MEW

Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound

Summary for 1MEW

Related1AK5 1ME7 1ME8 1ME9 1MEH 1MEI
DescriptorINOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, POTASSIUM ION, XANTHOSINE-5'-MONOPHOSPHATE, ... (5 entities in total)
Functional Keywordsalpha beta barrel, oxidoreductase
Biological sourceTritrichomonas foetus
Total number of polymer chains1
Total molecular weight56607.75
Authors
Prosise, G.L.,Luecke, H. (deposition date: 2002-08-08, release date: 2003-08-12, Last modification date: 2011-07-13)
Primary citation
Prosise, G.L.,Luecke, H.
Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
J.Mol.Biol., 326:517-527, 2003
PubMed: 12559919 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(02)01383-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.15 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers70.6%2.5%13.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report