5GUP
| Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | 著者 | Gu, J, Wu, M, Guo, R, Yang, M. | 登録日 | 2016-08-30 | 公開日 | 2017-03-29 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of Mammalian Respiratory Supercomplex I1III2IV1 Cell, 167, 2016
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5XTH
| Cryo-EM structure of human respiratory supercomplex I1III2IV1 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | 著者 | Gu, J, Wu, M, Yang, M. | 登録日 | 2017-06-19 | 公開日 | 2017-09-13 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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4D6T
| Cytochrome bc1 bound to the 4(1H)-pyridone GW844520 | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 3-chloro-2,6-dimethyl-5-{4-[4-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol, CARDIOLIPIN, ... | 著者 | Capper, M.J, O'Neill, P.M, Fisher, N, Strange, R.W, Moss, D, Ward, S.A, Berry, N.G, Lawrenson, A.S, Hasnain, S.S, Biagini, G.A, Antonyuk, S.V. | 登録日 | 2014-11-14 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | 主引用文献 | Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1. Proc.Natl.Acad.Sci.USA, 112, 2015
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6NHG
| Rhodobacter sphaeroides Mitochondrial respiratory chain complex | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Xia, D, Zhou, F, Esser, L. | 登録日 | 2018-12-21 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of bacterial cytochromebc1in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit. J.Biol.Chem., 294, 2019
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8E73
| Vigna radiata supercomplex I+III2 (full bridge) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Maldonado, M, Letts, J.A. | 登録日 | 2022-08-23 | 公開日 | 2023-01-11 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Plant-specific features of respiratory supercomplex I + III 2 from Vigna radiata. Nat.Plants, 9, 2023
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6XVF
| Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021 | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Amporndanai, K, Hasnain, S.S, Antonyuk, S.V. | 登録日 | 2020-01-21 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites. Front Cell Infect Microbiol, 10, 2020
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8IOG
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3TGU
| Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | 著者 | Huang, L.-S, Yang, G.-F, Berry, E.A. | 登録日 | 2011-08-17 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex. J.Am.Chem.Soc., 134, 2012
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4D6U
| Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121 | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 3-chloro-6-(hydroxymethyl)-2-methyl-5-{4-[3-(trifluoromethoxy)phenoxy]phenyl}pyridin-4-ol, CARDIOLIPIN, ... | 著者 | Capper, M.J, ONeill, P.M, Fisher, N, Strange, R.W, Moss, D, Ward, S.A, Berry, N.G, Lawrenson, A.S, Hasnain, S.S, Biagini, G.A, Antonyuk, S.V. | 登録日 | 2014-11-14 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.09 Å) | 主引用文献 | Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1. Proc.Natl.Acad.Sci.USA, 112, 2015
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2BCC
| STIGMATELLIN-BOUND CYTOCHROME BC1 COMPLEX FROM CHICKEN | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.I, Kim, K.K, Hung, L.W, Crofts, A.R, Berry, E.A, Kim, S.H. | 登録日 | 1998-09-18 | 公開日 | 1999-08-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Electron Transfer by Domain Movement in Cytochrome Bc1 Nature, 392, 1998
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4U3F
| Cytochrome bc1 complex from chicken with designed inhibitor bound | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CARDIOLIPIN, ... | 著者 | Huang, L.-S, Zhu, X.-L, Yang, G.F, Berry, E.A. | 登録日 | 2014-07-21 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2312 Å) | 主引用文献 | Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization Sci Rep, 5, 2015
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4PD4
| Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, ... | 著者 | Birth, D, Kao, W.-C, Hunte, C. | 登録日 | 2014-04-17 | 公開日 | 2014-06-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action. Nat Commun, 5, 2014
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1EZV
| STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT | 分子名称: | 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CYTOCHROME B, CYTOCHROME C1, ... | 著者 | Hunte, C, Koepke, J, Lange, C, Rossmanith, T, Michel, H. | 登録日 | 2000-05-12 | 公開日 | 2001-05-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Structure Fold.Des., 8, 2000
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2A06
| Bovine cytochrome bc1 complex with stigmatellin bound | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, AZIDE ION, CARDIOLIPIN, ... | 著者 | Huang, L.S, Cobessi, D, Tung, E.Y, Berry, E.A. | 登録日 | 2005-06-16 | 公開日 | 2005-06-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Binding of the Respiratory Chain Inhibitor Antimycin to the Mitochondrial bc(1) Complex: A New Crystal Structure Reveals an Altered Intramolecular Hydrogen-bonding Pattern. J.Mol.Biol., 351, 2005
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8EC0
| III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ... | 著者 | Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W. | 登録日 | 2022-08-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex. Nat Commun, 14, 2023
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8E7S
| III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 | 分子名称: | (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ... | 著者 | Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W. | 登録日 | 2022-08-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex. Nat Commun, 14, 2023
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2YBB
| Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, CARDIOLIPIN, ... | 著者 | Althoff, T, Mills, D.J, Popot, J.-L, Kuehlbrandt, W. | 登録日 | 2011-03-02 | 公開日 | 2011-10-19 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (19 Å) | 主引用文献 | Arrangement of Electron Transport Chain Components in Bovine Mitochondrial Supercomplex I(1)III(2)Iv(1). Embo J., 30, 2011
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5XTE
| Cryo-EM structure of human respiratory complex III (cytochrome bc1 complex) | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, ... | 著者 | Gu, J, Wu, M, Yang, M. | 登録日 | 2017-06-19 | 公開日 | 2017-08-30 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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5KLV
| Structure of bos taurus cytochrome bc1 with fenamidone inhibited | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ... | 著者 | Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z. | 登録日 | 2016-06-25 | 公開日 | 2016-10-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | 主引用文献 | Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III. J.Biol.Chem., 291, 2016
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7TAY
| Bos Taurus Mitochondrial BC1 in complex with Pyramoxadone | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ... | 著者 | Xia, D, Zhou, F, Esser, L. | 登録日 | 2021-12-21 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Conformation Switch of Rieske ISP subunit is revealed by the Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin to be published
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7TZ6
| Structure of mitochondrial bc1 in complex with ck-2-68 | 分子名称: | 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ... | 著者 | Xia, D, Esser, L, Zhou, F, Huang, R. | 登録日 | 2022-02-15 | 公開日 | 2023-02-22 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes. J.Biol.Chem., 299, 2023
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6T0B
| The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ... | 著者 | Marechal, A, Pinotsis, N, Hartley, A. | 登録日 | 2019-10-02 | 公開日 | 2020-04-22 | 最終更新日 | 2020-05-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes. Proc.Natl.Acad.Sci.USA, 117, 2020
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5OKD
| Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911. | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V. | 登録日 | 2017-07-25 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery. IUCrJ, 5, 2018
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5XTI
| Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | 著者 | Gu, J, Wu, M, Yang, M. | 登録日 | 2017-06-19 | 公開日 | 2017-09-13 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (17.4 Å) | 主引用文献 | Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
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2FYU
| Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor | 分子名称: | (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE, Cytochrome b, Cytochrome c1, ... | 著者 | Xia, D, Esser, L. | 登録日 | 2006-02-08 | 公開日 | 2006-08-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Surface-modulated motion switch: Capture and release of iron-sulfur protein in the cytochrome bc1 complex. Proc.Natl.Acad.Sci.Usa, 103, 2006
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