5OKD

Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911.

Summary for 5OKD

• Entry DOI: 10.2210/pdb5okd/pdb
• Descriptor: Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, TETRAETHYLENE GLYCOL, ... (22 entities in total)
• Functional Keywords: electron transport, antimalarial inhibitor, qi site binder
• Biological source: Bos taurus (Bovine); More
• Cellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P31800 P23004; Mitochondrion inner membrane: P00130 P00129 P13271 P00126; Mitochondrion inner membrane ; Multi-pass membrane protein : P00157; Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side: P00125; Mitochondrion inner membrane ; Single-pass membrane protein : P13272 P13272
• Total number of polymer chains: 10
• Total formula weight: 259445.61

Authors

Amporndanai, K.,O'Neill, P.M.,Hasnain, S.S.,Antonyuk, S.V. (deposition date: 2017-07-25, release date: 2018-02-28, Last modification date: 2024-01-17)

• Primary citation: Amporndanai, K.,Johnson, R.M.,O'Neill, P.M.,Fishwick, C.W.G.,Jamson, A.H.,Rawson, S.,Muench, S.P.,Hasnain, S.S.,Antonyuk, S.V.; X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.; IUCrJ, 5:200-210, 2018; PubMed: 29765610; DOI: 10.1107/S2052252518001616

Experimental method

X-RAY DIFFRACTION (3.1 Å)