4D6U

Cytochrome bc1 bound to the 4(1H)-pyridone GSK932121

Summary for 4D6U

• Entry DOI: 10.2210/pdb4d6u/pdb
• Related: 4D6T
• Descriptor: CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL, ... (20 entities in total)
• Functional Keywords: oxidoreductase, membrane protein, complex
• Biological source: BOS TAURUS (CATTLE); More
• Total number of polymer chains: 20
• Total formula weight: 573439.65

Authors

Capper, M.J.,ONeill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V. (deposition date: 2014-11-14, release date: 2015-01-14, Last modification date: 2023-12-20)

• Primary citation: Capper, M.J.,O'Neill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V.; Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1.; Proc.Natl.Acad.Sci.USA, 112:755-, 2015; PubMed: 25564664; DOI: 10.1073/PNAS.1416611112

Experimental method

X-RAY DIFFRACTION (4.09 Å)