4D6T
Cytochrome bc1 bound to the 4(1H)-pyridone GW844520
Summary for 4D6T
Entry DOI | 10.2210/pdb4d6t/pdb |
Related | 4D6U |
Descriptor | CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL, ... (19 entities in total) |
Functional Keywords | electron transport, cytochrome bc1, pyridone, membrane protein, complex |
Biological source | BOS TAURUS (CATTLE) More |
Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P31800 P23004 P23004 Mitochondrion inner membrane; Single-pass membrane protein: P13272 P13272 Mitochondrion inner membrane ; Multi-pass membrane protein : P00157 Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side: P00125 Mitochondrion inner membrane: P00129 P13271 P00126 P00130 |
Total number of polymer chains | 20 |
Total formula weight | 561767.54 |
Authors | Capper, M.J.,O'Neill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V. (deposition date: 2014-11-14, release date: 2015-01-14, Last modification date: 2023-12-20) |
Primary citation | Capper, M.J.,O'Neill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V. Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1. Proc.Natl.Acad.Sci.USA, 112:755-, 2015 Cited by PubMed: 25564664DOI: 10.1073/PNAS.1416611112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.57 Å) |
Structure validation
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