4U3F

Cytochrome bc1 complex from chicken with designed inhibitor bound

Summary for 4U3F

• Entry DOI: 10.2210/pdb4u3f/pdb
• Related: 3tgu
• Descriptor: Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i, Mitochondrial ubiquinol-cytochrome c reductase 7.2 kda protein, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... (21 entities in total)
• Functional Keywords: cytochrome bc1, membrane protein, heme protein, rieske iron sulfur protein, cytochrome b, cytochrome c1, ubiquinone, complex iii, strobilurins, azoxystrobin, stigmatellin, oxidoreductase, redox enzyme respiratory chain, electron transport, heme, inner membrane, membrane binding, mitochondrion, transmembrane, iron, mitochondrial inner membrane, respiratory chain, 2fe-2s, iron-sulfur, metal-binding, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Gallus gallus (Chicken); More
• Total number of polymer chains: 20
• Total formula weight: 492105.29

Authors

Huang, L.-S.,Zhu, X.-L.,Yang, G.F.,Berry, E.A. (deposition date: 2014-07-21, release date: 2015-07-29, Last modification date: 2023-09-27)

• Primary citation: Hao, G.-F.,Yang, S.-G.,Huang, W.,Wang, L.,Shen, Y.-Q.,Tu, W.-L.,Li, H.,Huang, L.-S.,Wu, J.-W.,Berry, E.A.,Yang, G.-F.; Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization; Sci Rep, 5:-, 2015; DOI: 10.1038/srep13471

Experimental method

X-RAY DIFFRACTION (3.2312 Å)