6XVF

Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021

Summary for 6XVF

• Entry DOI: 10.2210/pdb6xvf/pdb
• Descriptor: Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, TETRAETHYLENE GLYCOL, ... (22 entities in total)
• Functional Keywords: cytochrome bc1, malaria, electron transport, membrane protein
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 10
• Total formula weight: 238215.60

Authors

Amporndanai, K.,Hasnain, S.S.,Antonyuk, S.V. (deposition date: 2020-01-21, release date: 2020-07-22, Last modification date: 2024-01-24)

• Primary citation: McPhillie, M.J.,Zhou, Y.,Hickman, M.R.,Gordon, J.A.,Weber, C.R.,Li, Q.,Lee, P.J.,Amporndanai, K.,Johnson, R.M.,Darby, H.,Woods, S.,Li, Z.H.,Priestley, R.S.,Ristroph, K.D.,Biering, S.B.,El Bissati, K.,Hwang, S.,Hakim, F.E.,Dovgin, S.M.,Lykins, J.D.,Roberts, L.,Hargrave, K.,Cong, H.,Sinai, A.P.,Muench, S.P.,Dubey, J.P.,Prud'homme, R.K.,Lorenzi, H.A.,Biagini, G.A.,Moreno, S.N.,Roberts, C.W.,Antonyuk, S.V.,Fishwick, C.W.G.,McLeod, R.; Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.; Front Cell Infect Microbiol, 10:203-203, 2020; PubMed: 32626661; DOI: 10.3389/fcimb.2020.00203

Experimental method

X-RAY DIFFRACTION (3.5 Å)