6XVF
Crystal structure of bovine cytochrome bc1 in complex with tetrahydro-quinolone inhibitor JAG021
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome b-c1 complex subunit 1, mitochondrial | polymer | 445 | 49165.2 | 1 | UniProt (P31800) Pfam (PF00675) Pfam (PF05193) | Bos taurus (cattle) | Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1 |
| 2 | B (B) | Cytochrome b-c1 complex subunit 2, mitochondrial | polymer | 418 | 44495.0 | 1 | UniProt (P23004) Pfam (PF00675) Pfam (PF05193) | Bos taurus (cattle) | Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2 |
| 3 | C (C) | Cytochrome b | polymer | 378 | 42489.1 | 1 | UniProt (P00157) Pfam (PF00033) Pfam (PF00032) | Bos taurus (cattle) | Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 4 | D (D) | Cytochrome c1, heme protein, mitochondrial | polymer | 239 | 27107.0 | 1 | UniProt (P00125) Pfam (PF02167) | Bos taurus (cattle) | Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1 |
| 5 | E (E) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 196 | 21640.6 | 1 | UniProt (P13272) Pfam (PF02921) Pfam (PF00355) | Bos taurus (cattle) | Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Rieske protein UQCRFS1,Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 6 | F (F) | Cytochrome b-c1 complex subunit 7 | polymer | 100 | 12485.2 | 1 | UniProt (P00129) Pfam (PF02271) | Bos taurus (cattle) | Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein |
| 7 | G (G) | Cytochrome b-c1 complex subunit 8 | polymer | 74 | 8799.2 | 1 | UniProt (P13271) Pfam (PF02939) | Bos taurus (cattle) | Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C |
| 8 | H (H) | Cytochrome b-c1 complex subunit 6, mitochondrial | polymer | 64 | 7515.4 | 1 | UniProt (P00126) Pfam (PF02320) | Bos taurus (cattle) | Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein |
| 9 | I (I) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 46 | 4827.6 | 1 | UniProt (P13272) Pfam (PF09165) | Bos taurus (cattle) | Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Rieske protein UQCRFS1,Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 10 | J (J) | Cytochrome b-c1 complex subunit 9 | polymer | 59 | 6866.9 | 1 | UniProt (P00130) Pfam (PF05365) | Bos taurus (cattle) | Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein |
| 11 | K, S, T (A, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) PubChem (8200) | |||
| 12 | L (A) | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE | non-polymer | 410.4 | 1 | Chemie (6PE) PubChem (49866560) | |||
| 13 | DA, GA, HA, IA, JA... (E, F, G, A, B...) | PHOSPHATE ION | non-polymer | 95.0 | 9 | Chemie (PO4) PubChem (1061) | |||
| 14 | AA, FA, N, U (D, E, A, C) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 15 | P, Q (C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 16 | R (C) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 17 | EA, V (E, C) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 2 | Chemie (PEE) PubChem (108229) PubChem (44891344) PubChem (54095275) PubChem (14238554) PubChem (5909904) PubChem (9546757) PubChem (6437392) PubChem (99655478) PubChem (99655479) PubChem (9546744) PubChem (138113035) PubChem (171729549) | |||
| 18 | W (C) | 2-methyl-3-[4-[4-(trifluoromethyloxy)phenoxy]phenyl]-5,6,7,8-tetrahydro-3~{H}-quinolin-4-one | non-polymer | 415.4 | 1 | Chemie (JAG) PubChem (146681111) | |||
| 19 | Y (D) | HEME C | non-polymer | 618.5 | 1 | Chemie (HEC) | |||
| 20 | BA (E) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 1 | Chemie (FES) | |||
| 21 | CA (E) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 1 | Chemie (PX4) PubChem (26198) PubChem (87505) PubChem (5313082) | |||
| 22 | KA, LA, MA, NA, OA... (A, B, C, D, F...) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 225391.3 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 12824.3 | |
| All* | Total formula weight | 238215.6 |
