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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

An explanation article covering one of the proteins of this virus is available on the "Molecules of the Month" page below:

The tab "All entries" contains all PDB IDs, in case you want to check all independent entries, including group depositions by the same authors. The "Repr. entries" tab contains only representative PDB entries with the highest resolution, excluding duplicate entries with 100% amino acid sequence identitiy, even if they contain a different ligand. Finally, the "Latest entries" tab contains the latest entries released this week.


Created: 2020-10-28 (last edited: more than 1 year ago)2022-09-02
7VBE
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BU of 7vbe by Molmil
1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
Descriptor: Nucleoprotein
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-08-31
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
To Be Published
7VBF
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BU of 7vbf by Molmil
1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5
Descriptor: Nucleoprotein
Authors:Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
Deposit date:2021-08-31
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:1.3 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 8.5
To Be Published
7X1M
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BU of 7x1m by Molmil
The complex structure of Omicron BA.1 RBD with BD604, S309,and S304
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab heavy chain, BD-604 Fab light chain, ...
Authors:Huang, M, Xie, Y.F, Qi, J.X.
Deposit date:2022-02-24
Release date:2022-07-06
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3.
Immunity, 55, 2022
7XAZ
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BU of 7xaz by Molmil
Crystal structure of Omicron BA.1.1 RBD complexed with hACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Liao, H, Meng, Y, Li, W.
Deposit date:2022-03-19
Release date:2022-07-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
7XB0
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BU of 7xb0 by Molmil
Crystal structure of Omicron BA.2 RBD complexed with hACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L, Liao, H, Meng, Y, Li, W.
Deposit date:2022-03-19
Release date:2022-07-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
7XB1
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BU of 7xb1 by Molmil
Crystal structure of Omicron BA.3 RBD complexed with hACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, W, Meng, Y, Liao, H.
Deposit date:2022-03-19
Release date:2022-07-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
7Y42
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BU of 7y42 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein in complex with all-trans retinoic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RETINOIC ACID, Spike glycoprotein
Authors:Xiang, Y, Wang, L.
Deposit date:2022-06-13
Release date:2022-07-06
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:A Retinol Derivative Inhibits SARS-CoV-2 Infection by Interrupting Spike-Mediated Cellular Entry.
Mbio, 13, 2022
8CWU
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BU of 8cwu by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 1-21
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VHH 1-21
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-05-19
Release date:2022-07-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CWV
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BU of 8cwv by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 2-31 and a human antibody CC12.1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-05-19
Release date:2022-07-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CXN
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BU of 8cxn by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-57
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, pan-sarbecovirus nanobody 2-57
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-22
Release date:2022-07-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CXQ
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BU of 8cxq by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-22
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 1-22
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-22
Release date:2022-07-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CY6
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BU of 8cy6 by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-65
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 2-65
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CY7
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BU of 8cy7 by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CY9
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BU of 8cy9 by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-23
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 1-23
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CYA
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BU of 8cya by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-67
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CYB
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BU of 8cyb by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 1-8
Descriptor: 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CYC
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BU of 8cyc by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 2-34
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CYD
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BU of 8cyd by Molmil
SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-45
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 2-45
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8CYJ
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BU of 8cyj by Molmil
RBD of SARS-CoV-2 Spike protein in complex with pan-sarbecovirus nanobodies 2-10, 2-67, 2-62 and 1-25
Descriptor: Spike glycoprotein, pan-sarbecovirus nanobody 1-25, pan-sarbecovirus nanobody 2-10, ...
Authors:Huang, W, Taylor, D.
Deposit date:2022-05-23
Release date:2022-07-06
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Superimmunity by pan-sarbecovirus nanobodies.
Cell Rep, 39, 2022
8DCC
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BU of 8dcc by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 3 Bound to P2B-2F6 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B-2F6 Fab heavy chain, P2B-2F6 Fab light chain, ...
Authors:Dickey, T.D, Tolia, N.H.
Deposit date:2022-06-16
Release date:2022-07-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022
7FB3
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BU of 7fb3 by Molmil
SARS-CoV-2 spike protein in one-RBD weak state after CTSL-treatment
Descriptor: Spike glycoprotein
Authors:Zhu, Y, Tai, L.H, Sun, F.
Deposit date:2021-07-08
Release date:2022-07-13
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Novel sites for Cathepsin L cleavage in SARS-CoV-2 spike guide treatment strategies
To Be Published
7FBJ
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BU of 7fbj by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing nanobody 17F6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, ...
Authors:Zhu, J, Xu, T, Feng, B, Liu, J.
Deposit date:2021-07-11
Release date:2022-07-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
7FBK
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BU of 7fbk by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain N501Y mutant in complex with neutralizing nanobody 20G6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, Spike protein S1
Authors:Zhu, J, Xu, T, Feng, B, Liu, J.
Deposit date:2021-07-11
Release date:2022-07-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
7P19
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BU of 7p19 by Molmil
Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Erausquin, E, Lopez-Sagaseta, J.
Deposit date:2021-07-01
Release date:2022-07-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural bases for the higher adherence to ACE2 conferred by the SARS-CoV-2 spike Q498Y substitution.
Acta Crystallogr D Struct Biol, 78, 2022
7WJY
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BU of 7wjy by Molmil
Omicron spike trimer with 6m6 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ...
Authors:Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
Deposit date:2022-01-08
Release date:2022-07-13
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022

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