7XB1
Crystal structure of Omicron BA.3 RBD complexed with hACE2
Summary for 7XB1
Entry DOI | 10.2210/pdb7xb1/pdb |
Descriptor | Angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | sars-cov-2, omicron, rbd, hace2, complex structure, viral protein, hydrolase-viral protein complex, hydrolase/viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 93681.27 |
Authors | |
Primary citation | Li, L.,Liao, H.,Meng, Y.,Li, W.,Han, P.,Liu, K.,Wang, Q.,Li, D.,Zhang, Y.,Wang, L.,Fan, Z.,Zhang, Y.,Wang, Q.,Zhao, X.,Sun, Y.,Huang, N.,Qi, J.,Gao, G.F. Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell, 185:2952-2960.e10, 2022 Cited by PubMed: 35809570DOI: 10.1016/j.cell.2022.06.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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